Omega 3 Fatty Acids in Patients With Chronic Renal Disease

Last updated: July 30, 2019
Sponsor: University of Chile
Overall Status: Completed

Phase

3

Condition

Nephropathy

Kidney Failure (Pediatric)

Renal Failure

Treatment

N/A

Clinical Study ID

NCT03280615
Omegarenal
  • Ages 18-80
  • All Genders

Study Summary

To study the tolerance and efficacy of an omega 3 fatty acids supplement on renal and vascular function and inflammatory parameters in patients with chronic renal disease

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Urinary albumin excretion over 30 mg/g creatinin

  • Chronic renal failure stage 2 to 4

  • Absence of serious conditions such as cáncer, decompensated heart failure, chronicinfections and severe arterial lesions

Exclusion

Exclusion Criteria:

  • Blood glucose levels over 180 mg/dl or glycosilated hemoglobin over 8%

  • Presence of cognitive impairment that does not allow to sigin a written informedconsent

  • Alcohol or illicit drug abuse

Study Design

Total Participants: 100
Study Start date:
September 20, 2017
Estimated Completion Date:
October 31, 2018

Study Description

In a double blind trial in patients with chronic renal disease, the effects of a 3.7 g supplement of docosahexanoic and eicosapentanoic acids or a supplement of a similar dose of corn oil during 12 weeks, will be assessed on the following parameters:

  1. Urine albumin excretion

  2. Renal function measured with serum creatinine, cystatin C and beta-2 microglobulin

  3. Carotid intima media thickness and pulse wave velocity

  4. Inflammation status assessed measuring serum levels of C reactive protein and interleukin 6

  5. Metabolic control of diabetes

  6. Serum lipid levels

Connect with a study center

  • Institute of Nutrition and Food Technology University of Chile

    Santiago, Metropolitana
    Chile

    Site Not Available

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