Amiodarone Usage After Ischemic Ventricular Tachycardia Ablation

Last updated: August 5, 2017
Sponsor: Yuksek Ihtisas Hospital
Overall Status: Trial Status Unknown

Phase

N/A

Condition

Fast Heart Rate (Tachycardia)

Coronary Artery Disease

Congestive Heart Failure

Treatment

N/A

Clinical Study ID

NCT03244748
ozcan01
  • Ages > 18
  • All Genders

Study Summary

Ventricular Tachycardia ablation in ischemic cardiomyopathy patients is required procedure in cases when anti-arrhythmic drugs failed. The concern is if adjunctive continuation amiodarone after ablation is needed.

Eligibility Criteria

Inclusion

Inclusion Criteria: Ischemic cardiomyopathy patients applied with frequent ICD interventionor electrical stormsand having ejection fraction below 50%. Frequent ICD defined as more than 1 ICDintervention within month. Electrical storm defined as more than 2 ICD intervention withinone day.

Exclusion

Exclusion Criteria: Patients with cardiomyopathies other than ischemic etiology

Study Design

Total Participants: 100
Study Start date:
January 01, 2016
Estimated Completion Date:
March 01, 2018

Study Description

Ischemic cardiomyopathy patients have implantable cardioverter defibrillators (ICD) to prevent arrhythmic deaths. Ventricular tachycardia (VT) events with frequent ICD interventions in ischemic cardiomyopathy patients is encountered frequently. Frequents ICD interventions is associated with worse outcomes. Anti-arrhythmic drugs ,mostly amiodarone, are given prevent ventricular arrhythmias and ICD interventions that may not be curative. Ablation of ventricular tachycardia is the suggested treatment when anti-drugs are without effect. After ablation of ventricular arrhythmia the continuation of amiodarone is not well elucidated.

In this study we aimed to enroll ischemic cardiomyopathy patients having frequent ICD interventions despite medical treatment. VT ablation is performed and patients divided into two groups; group one continues having amiodarone after ablation, group two does not have amiodarone after ablation. Both groups will be compared in terms of recurrence and death.

Connect with a study center

  • Turkiye Yuksek Ihtisas Training and Research Hospital

    Ankara, 06590
    Turkey

    Active - Recruiting

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.