Modulating Movement Intention Via Cortical Stimulation

Inclusion Criteria:

(Healthy Controls)

• Fluent in English

(Patients with PMD or PNES):

• Diagnosis of PMD/PNES confirmed by a neurologist with expertise in movementdisorders.

• Per the treating neurologist, subject is unlikely to require treatment and/or dosagechanges for 3-6 months following screening

Exclusion Criteria:

• Any history of a significant neurological disorder, which may interfere with theinterpretation of study data, as determined by the PI

• Chronic or progressive medical condition

• Any history of traumatic brain injury or significant head trauma

• Currently meets criteria for substance abuse or dependence

• History of any psychotic disorder or other psychiatric condition which may interferewith data interpretation

• Pregnancy

• Metal or devices in the head, including neurostimulators or metal foreign bodies

• Any other implanted metal device, including pacemaker, spinal cord stimulator, VNS.

• Any other ferromagnetic substance in the body that may increase study risk (including dental prosthetics, etc.).

• Taking tricyclic antidepressant or antiepileptic medications or CNS active drugsunder "strong potential hazard" list in Rossi et al., 2009

• Current diagnosis of any inflammatory or autoimmune disorder within last 6 months

PMD and PNES Patients

• Any history of traumatic brain injury or significant head trauma

• Diagnosis of organic seizure disorder, including febrile seizures and tonic-clonicseizures;

• Neurological disorder other than PMD and PNES including stroke, fainting spells orsyncope of unknown cause(s);

• Major or unstable medical illness, especially any current diagnosis of inflammatoryor autoimmune disorders within last 6 months

• Metal or devices in the head, including neurostimulators or metal foreign bodies

• Taking tricyclic antidepressant medications or CNS active drugs under "strongpotential hazard" list in Rossi et al., 2009;

• Diagnosis of dementia, or Montreal Cognitive Assessment (MoCA) ≤24;

• Recurrent visual hallucinations, within the past 6 months;

• History of significant uncontrollable movements of the head;

• Any clinically significant abnormality on vital signs