Software Monitoring of Treatment Related Toxicities in Advanced Renal Cell Carcinoma

Inclusion Criteria:

• Diagnosis of histologically confirmed renal cell carcinoma of any subtype witheither pathological or radiographic evidence of metastatic disease

• Greater than 18 years of age

• A participating Wilmot Cancer Center oncologist has determined that candidate shouldbe started on either oral targeted therapy or immunotherapy for treatment of theiradvanced RCC; this can be for first-line or any subsequent line therapy

• Able to provide written informed consent

• Proficient in the English language and self-reports as literate

• Must have an active email address or access to a smart device on which text messagescan be received

Exclusion Criteria:

• Women cannot be breast-feeding

• Does not have regular access to the internet

• Unable to come to the Wilmot Cancer Center for appointments every 3-4 months forroutine visits with their primary oncologist

• Subjects who were on the study previously will not be allowed to re-enroll in theevent of a treatment change