The Effect of Transcranial Direct Current Stimulation (tDCS) on Depression in PD

Last updated: October 22, 2018
Sponsor: Inje University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Depression

Dyskinesias

Parkinson's Disease

Treatment

N/A

Clinical Study ID

NCT03227783
17-0051
  • Ages > 19
  • All Genders

Study Summary

Depression is common in Parkinson's disease (PD), but the effective treatment is not established yet. tDCS is a non-invasive brain stimulation to modulate brain function. The tDCS on the depression in general population were already conducted, but not in PD. This study is to know whether transcranial direct current stimulation (tDCS) is effective for the treatment of depression in PD. Participant will be asked to visit three consecutive days for the non-invasive stimulation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • UK Parkinson's disease brain bank criteria

  • more than 19 years old

  • Able to provide consent for the protocol

  • Depression (based on DSM-IV criteria)

Exclusion

Exclusion Criteria:

  • Dementia

  • Unpredictable symptom fluctuations

  • Contraindication to tDCS (i) irritations, cuts, lesions in the brain (ii) anypreexisting unstable medical conditions, or conditions that may increase the risk ofstimulation such as uncontrolled epilepsy (iii) history of severe cranial trauma withalteration of the cranial anatomy or metallic intracranial implants (iv) history ofseizure

  • Subjects without the capacity to give informed consent

  • If participation in the study would, in the opinion of the investigators, cause unduerisk or stress for reasons such as excessive fatigue, general frailty, or excessiveapprehension

Study Design

Total Participants: 26
Study Start date:
February 01, 2019
Estimated Completion Date:
December 31, 2021

Connect with a study center

  • Inje university, Busan Paik Hospital

    Busan,
    Korea, Republic of

    Active - Recruiting

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