Effect of Myomectomy for Intramural Myoma on Fertility Outcomes in Infertile Women

Phase

N/A

Condition

Infertility

Uterina Myoma

Treatment

N/A

Clinical Study ID

NCT03143114

WR3

Ages 20-33
Female

Study Summary

The aim of this study is to evaluate the effect of myomectomy for intramural myomas on the fertility outcomes in infertile women.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Infertility for at least one year.
Presence of intramural myoma.
Absence of any other cause of infertility as revealed by basic infertility work upincluding laparoscopy.

Exclusion

Exclusion Criteria:

Age is < 20 or > 33 years.
Symptomatic fibroid causing pelviabdominal swelling.
Presence of > 2 myomas.
Presence of a coexisting another type of myoma other than intramural myoma (e.g.submucosal, subserosal, cervical or ligamentary myoma).
Presence of any other cause of infertility.

Study Design

May 15, 2017

June 15, 2021

Study Description

All women participating in the study will be randomly allocated into two groups; myomectomy group and conservative management group. Women in the myomectomy group will be subjected to laparotomy to remove the myomas while women in the conservative management group will not be subjected to surgery. Women in the myomectomy group will be asked to abstain from having sexual intercourse (or use a barrier contraception method) for 3 months after surgery then to start having regular fertility-oriented intercourse after that. Women in the conservative management group will be asked to immediately start having regular fertility-oriented intercourse. Women in both groups will be monitored form the time of starting regular intercourse and for one year for occurrence of clinical pregnancy.

Connect with a study center

Obstetrics and Gynecology Department in Mansoura University Hospital
Mansoura, Dakahlia 35111
Egypt
Site Not Available
Obstetrics and Gynecology Department in Mansoura University Hospital
Mansourah, Dakahlia 35111
Egypt
Active - Recruiting
Obstetrics and Gynecology Department in Mansoura University
Port Said,
Egypt
Active - Recruiting

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