German MPN-Registry for BCR-ABL 1-Negative Myeloid Neoplasms (Study Group Ulm)

Last updated: May 17, 2023
Sponsor: University of Ulm
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neoplasms

Treatment

Registry study

Clinical Study ID

NCT03125707
MPN Registry - Ulm
  • Ages > 18
  • All Genders

Study Summary

To register a large number of patients with the diagnosis of a BCR-ABL 1- negative myeloid neoplasm (according to WHO 2008 / 2016 classification) in participating centers

To store samples from all patients (e.g. bone marrow aspirate, peripheral blood, plasma, and buccal swap, skin biopsy samples in exceptional cases)

To perform morphologic and genetic analyses

To assess clinical characteristics and outcome data using a defined catalogue containing clinically relevant variables

To assess biological disease features and correlate with clinical outcome data (prognostic and predictive markers)

To assess quality of life

Eligibility Criteria

Inclusion

Inclusion Criteria: Both female and male patients meeting the mentioned inclusion criteria will be included inthis registry, because the risk to get a myeloid neoplasm does not depend on a patient'sgender. Patients must meet all of the following inclusion criteria to be eligible forenrollment into the registry:

  • Patients with BCR-ABL 1-myeloid neoplasia according to WHO classification or IWG MRIcriteria
  • Age ≥ 18 years. There is no upper age limit.
  • Signed written informed consent.

Exclusion

Exclusion Criteria:

  • Severe neurological or psychiatric disorder interfering with ability to give aninformed consent
  • No consent for registration, storage and handling of the personal data

Study Design

Total Participants: 2172
Treatment Group(s): 1
Primary Treatment: Registry study
Phase:
Study Start date:
May 01, 2013
Estimated Completion Date:
September 30, 2045

Study Description

To register a large number of patients with the diagnosis of a BCR-ABL 1- negative myeloid neoplasm (according to WHO 2008 / 2016 classification) in participating centers

To store samples from all patients (e.g. bone marrow aspirate, peripheral blood, plasma, and buccal swap, skin biopsy samples in exceptional cases)

To perform morphologic and genetic analyses

To assess clinical characteristics and outcome data using a defined catalogue containing clinically relevant variables

To assess biological disease features and correlate with clinical outcome data (prognostic and predictive markers)

To assess quality of life

Connect with a study center

  • Hämatologische Onkologie Praxis Augsburg

    Augsburg, 86150
    Germany

    Active - Recruiting

  • Klinikum Augsburg

    Augsburg, 86156
    Germany

    Active - Recruiting

  • Helios Klinikum, Bad Saarow

    Bad Saarow, 15526
    Germany

    Active - Recruiting

  • Klinikum Mittelbaden

    Baden-Baden, 76532
    Germany

    Active - Recruiting

  • MVZ Klinikum Coburg

    Coburg, 96450
    Germany

    Active - Recruiting

  • Donauwörth, Onko-Medeor

    Donauwörth, 86609
    Germany

    Active - Recruiting

  • Onkologie, BAG, Dresden

    Dresden, 01307
    Germany

    Active - Recruiting

  • Onkologie Erding

    Erding, 85435
    Germany

    Active - Recruiting

  • Universitätsklinikum Freiburg

    Freiburg, 79106
    Germany

    Active - Recruiting

  • Universitätsklinikum Greifswald

    Greifswald, 17475
    Germany

    Active - Recruiting

  • Alb Fils Kliniken Göppingen

    Göppingen, 73035
    Germany

    Active - Recruiting

  • Onkologische Praxis, Heidelberg

    Heidelberg, 69115
    Germany

    Site Not Available

  • Onkologische Schwerpunktpraxis Heilbronn

    Heilbronn, 74072
    Germany

    Active - Recruiting

  • Onkologische Schwerpunktpraxis, Heilbronn

    Heilbronn, 74072
    Germany

    Site Not Available

  • Marienhospital Bochum-Herne

    Herne, 44625
    Germany

    Active - Recruiting

  • Universitätsklinikum Jena

    Jena, 07743
    Germany

    Active - Recruiting

  • Klinikum Kempten-Oberallgäu gGmbH

    Kempten, 87439
    Germany

    Active - Recruiting

  • Landshut VK&K Studien GbR

    Landshut, 84036
    Germany

    Active - Recruiting

  • Leer, Studienzentrum Unter Ems

    Leer, 26789
    Germany

    Site Not Available

  • Universitätsklinikum Leipzig

    Leipzig, 04103
    Germany

    Active - Recruiting

  • Universitätsklinikum Magdeburg

    Magdeburg, 39120
    Germany

    Active - Recruiting

  • Universitätsmedizin Mainz

    Mainz, 55131
    Germany

    Site Not Available

  • Mannheim, Onkologiepraxis

    Mannheim, 68161
    Germany

    Active - Recruiting

  • Universitätsklinikum Mannheim

    Mannheim, 55131
    Germany

    Active - Recruiting

  • Memmingen, Onkologiepraxis

    Memmingen, 87700
    Germany

    Active - Recruiting

  • Mühlenkreiskliniken Minden

    Minden, 32429
    Germany

    Active - Recruiting

  • Stauferklinikum Schwäbisch Gmünd

    Mutlangen, 73557
    Germany

    Active - Recruiting

  • Diakonie-Klinikum Stuttgart

    Stuttgart, 70176
    Germany

    Active - Recruiting

  • Stuttgart, MVZ am RBK

    Stuttgart, 70376
    Germany

    Active - Recruiting

  • Universitätsklinikum Ulm

    Ulm, 89081
    Germany

    Active - Recruiting

  • Rems-Murr-Kliniken Winnenden

    Winnenden, 71334
    Germany

    Active - Recruiting

  • Würzburg / Kitzingen, Gemeinschaftspraxis Dr. Schlag

    Würzburg, 97080
    Germany

    Active - Recruiting

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