Impact of Enhanced External Counterpulsation on Vascular Hemodynamics and Status

Last updated: October 29, 2020
Sponsor: Sun Yat-sen University
Overall Status: Completed

Phase

N/A

Condition

Chest Pain

Vascular Diseases

Coronary Artery Disease

Treatment

N/A

Clinical Study ID

NCT03102502
EECP- 2
  • Ages 20-80
  • All Genders

Study Summary

The present study aimed to investigated the effect of Enhanced External Counterpulsation (EECP) on vascular hemodynamics and atherosclerosis, and the underlying shear stress related mechanisms

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • More than 50% stenosis of left main trunk and 3 epicardial coronary arteries and theirlarge branches showed by coronary angiography
  • Or history of myocardial infarction
  • Or history of prior revascularization
  • Signed informed consent to participate in the study

Exclusion

Exclusion Criteria:

  • Clinically significant valvular heart disease
  • Aortic aneurysm
  • Congenital heart disease
  • Acute myocarditis
  • Arrythmias significantly interfere with the triggering of the EECP device
  • History of cerebral hemorrhage
  • Hemorrhagic disease
  • Lower limb infection, phlebitis
  • Deep venous thrombosis
  • Malignant disease
  • INR > 2.5
  • Uncontrolled hypertension, defined as SBP > 180mmHg or DBP > 110mmHg
  • Pregnancy

Study Design

Total Participants: 110
Study Start date:
March 10, 2017
Estimated Completion Date:
January 10, 2019

Study Description

Patients with coronary heart disease will be randomized into two groups: standard medical treatment and standard medical treatment plus EECP intervention. Hemodynamic parameters, vascular status and function will be measured.

Connect with a study center

  • The First Affiliated Hospital, Sun Yat- sen University

    Guangzhou, Guangdong 510080
    China

    Site Not Available

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