Syndrome Differentiation in the Management of Chronic Stable Coronary Artery Disease (SCAD) to Improve Quality

Last updated: January 12, 2017
Sponsor: First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Overall Status: Trial Status Unknown

Phase

N/A

Condition

Cardiovascular Disease

Vascular Diseases

Chest Pain

Treatment

N/A

Clinical Study ID

NCT03018769
FirstTeachingHTianjinUTCM
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

1.1 To build a TCM diagnosis and treatment database for chronic stable CAD; 1.2 To summarize the pattern of TCM medicine used and the effect of the medication in chronic stable CAD.

1.3 To formulate a syndrome differentiation determined medicine plan based on the improvement in the quality of life on chronic stable CAD patients.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • without age limit

  • diagnose as chronic SCAD at first visit

  • heart function classification between II~III Canada classification(CCS)

  • Be willing to accept Chinese herbal decoction

  • sign an informed consent

Exclusion

Exclusion Criteria:

  • suffer from acute myocardial infarction (AMI) ,unstable angina or priorrevascularization(i.e PCI,CABG) in the latest 60 days .

  • have such diseases as follow: a.poorly controlled blood pressure even takenmedicine(systolic pressure≥180mmHg, diastolic pressure≥100mmHg); - severearrhythmia(atrial fibrillation with rapid ventricular response, atrial flutter,paroxysmal ventricular tachycardia, etc); c.pulmonary heart disease, rheumatic heartdisease, myocarditis, cardiomyopathy, aortic dissection, pulmonary embolism.

  • hyperthyreosis, cervical spondylosis, gallbladder-cardiac syndrome, gastroesophagealreflux, esophageal hiatal hernia, neurosis, climacteric syndrome and other diseaseswhich would cause chest pain.

  • alanine transaminase(ALT) or serum creatinine(Scr) more than twice the normalreference value.

  • hemoglobin(Hb)<100g/L or have severe hematological system disease.

  • malignant tumor.

  • pregnant, lactating women or other women have reproductive requirement.

  • psychosis or cognition impairment person.

  • taken chinese medicine decoction in recent two weeks.

  • not take part in any other clinical trail.

Study Design

Total Participants: 2000
Study Start date:
December 01, 2016
Estimated Completion Date:
December 31, 2017

Study Description

Chronic stable coronary artery disease (SCAD) is a general term for all kinds of coronary artery disease (CAD) which includes patients with chronic stable angina, oldmyocardial infarctions and also stable condition after revascularization (i.e percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG)). According to 2012 American Heart Association/American College of Cardiology (AHA/ACC) guide, the objective of the treatment for SCAD is to maintain or recover patients' exercise tolerance, quality of life and avoid complication like heart failure,so as to decrease mortality, eliminate symptoms and avoid adverse reactions.

Traditional Chinese medicine (TCM) has two thousand years of history in managing CAD and has its advantages in improving quality of life. Using scientific method to evaluate, demonstrate and conclude the clinical curative effect of TCM is an extremely important task for both TCM and Chinese and western integrative medicine win the treatment of CAD. Recent researches mainly focus on certain types or some certain pathological and physiological stages of CAD, worse still, different areas experts have their own experiences and opinions with the treatment. There is a lack of unified syndrome differentiation and prescriptions plan for the chronic stable CAD and not enough attention has been paid to TCM despite it having many advantages in improving quality of life in these patients. Considering all the above, this research studied past syndromes research results and real clinical effective chronic SCAD cases. Cases were analysed and explored, effective cases were filtered, syndrome differentiation of the prescriptions was refined, thus build a TCM diagnosis and treatment information database.

Connect with a study center

  • The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine

    Anhui,
    China

    Active - Recruiting

  • Beijing Hospital of Traditional Chinese Medicine

    Beijing,
    China

    Active - Recruiting

  • Dongfang Hospital of Beijing University of Chinese Medicine

    Beijing,
    China

    Active - Recruiting

  • Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

    Beijing,
    China

    Active - Recruiting

  • Guang'anmen Hospital of China Academy of Chinese Medical Sciences

    Beijing,
    China

    Active - Recruiting

  • Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Beijing,
    China

    Active - Recruiting

  • the third Affiliated to Beijing University of Chinese Medicine

    Beijing,
    China

    Active - Recruiting

  • Affiliated Hospital of Changchun University of Traditional Chinese Medicine

    Changchun,
    China

    Active - Recruiting

  • Affiliated Hospital of Gansu University of Chinese Medicine

    Gansu,
    China

    Active - Recruiting

  • Guangdong Provincial Hospital of Chinese Medicine

    Guangdong,
    China

    Active - Recruiting

  • Guangdong Second Troditional Chinese Medicine Hospital

    Guangdong,
    China

    Active - Recruiting

  • First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine

    Guangzhou,
    China

    Active - Recruiting

  • Heilongjiang Provincial Hospital of traditional Chinese Medicine

    Heilongjiang,
    China

    Active - Recruiting

  • Henan Province Hospital of TCM

    Henan,
    China

    Active - Recruiting

  • The First Affiliated Hospital of Henan University of TCM

    Henan,
    China

    Active - Recruiting

  • Affiliated Hospital of Hunan Academy of Chinese Medicine

    Hunan,
    China

    Active - Recruiting

  • The First Hospital of Hunan University of Chinese Medicine

    Hunan,
    China

    Active - Recruiting

  • The Second Affiliated Traditional hospital of Hunan University of Traditional Chinese Medicine

    Hunan,
    China

    Active - Recruiting

  • Jiangsu Province Hospital of TCM

    Jiangsu,
    China

    Active - Recruiting

  • Jiangxi Provincial Hospital of Chinese Medicine

    Jiangxi,
    China

    Active - Recruiting

  • Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

    Liaoning,
    China

    Active - Recruiting

  • The Second Affiliated Hospital of Liaoning University of traditional Chinese Medicine

    Liaoning,
    China

    Active - Recruiting

  • Shandong Province Hospital of Traditional Chinese Medicine

    Shandong,
    China

    Active - Recruiting

  • Shanxi Hospital of Traditional Chinese Medicine

    Shanxi,
    China

    Active - Recruiting

  • Shanxi Province Hospital of Traditional Chinese Medicine

    Shanxi,
    China

    Active - Recruiting

  • The Affiliated Hospital to Shanxi University of Traditional Chinese Medicine

    Shanxi,
    China

    Active - Recruiting

  • The Second Affiliated Hospital of Shanxi University of Traditional Chinese Medcine

    Shanxi,
    China

    Active - Recruiting

  • Shijiazhuang Traditional Chinese Medicine Hospita

    Shijiazhuang,
    China

    Active - Recruiting

  • First Teaching Hospital of Tianjin University of TCM

    Tianjin,
    China

    Active - Recruiting

  • Second Affiliated Hospital of Tianjin University of TCM

    Tianjin,
    China

    Active - Recruiting

  • Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital

    Tianjin,
    China

    Active - Recruiting

  • Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region

    Xinjiang,
    China

    Active - Recruiting

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