VCRC Tissue Repository

Last updated: February 11, 2025
Sponsor: University of Pennsylvania
Overall Status: Active - Recruiting

Phase

N/A

Condition

Connective Tissue Diseases

Lupus

Vascular Diseases

Treatment

N/A

Clinical Study ID

NCT02967068
VCRC5511
U54AR057319
  • All Genders

Study Summary

The purpose of this study is to collect existing tissue specimens from subjects enrolled in Vasculitis Clinical Research Consortium (VCRC) studies. Analysis of these tissue specimens and linked clinical data collected through VCRC studies may lead to the identification and development of a series of translational research projects. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • A participant will be deemed eligible for this study if the participant is/wasenrolled in another one of the VCRC observational/longitudinal protocols (5502, 5503, 5504, 5505, 5506, 5507, 5563) and/or one of the VCRC interventional studies (5522, 5523, 5526, 5527, or 5562).

Exclusion

Exclusion Criteria:

  • Inability to give informed consent (or their guardians in the case of children) andto sign the consent form.

  • Unwilling to allow the use of their tissue for research.

Study Design

Total Participants: 1000
Study Start date:
November 01, 2016
Estimated Completion Date:
December 31, 2027

Study Description

Biopsy specimens collected as standard of care for these diseases will be retrieved and used in research. The most common biopsies performed are kidney, lung, skin, nerves, and vessels; however, other tissue is also of interest for the study. Biopsies are not performed as part of this protocol, rather we will request consent to collect biopsy specimens already collected under routine care.

Connect with a study center

  • St. Joseph's Healthcare

    Hamilton, Ontario L8N 3B6
    Canada

    Active - Recruiting

  • University of Toronto Mount Sinai Hospital

    Toronto, Ontario M5G 1X5
    Canada

    Active - Recruiting

  • Boston University School of Medicine

    Boston, Massachusetts 02118
    United States

    Completed

  • Brigham and Women's Hospital

    Boston, Massachusetts 02115
    United States

    Completed

  • Cleveland Clinic

    Cleveland, Ohio 44195
    United States

    Active - Recruiting

  • University of Pennsylvania

    Philadelphia, Pennsylvania 19104
    United States

    Active - Recruiting

  • University of Pittsburgh

    Pittsburgh, Pennsylvania 15261
    United States

    Completed

  • University of Utah

    Salt Lake City, Utah 84132
    United States

    Completed

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