Whole Brain Vessel Wall Imaging in Stroke Patients (WISP): An International Multi-Center Registry

Last updated: August 13, 2018
Sponsor: Cedars-Sinai Medical Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Stroke

Thrombosis

Cerebral Ischemia

Treatment

N/A

Clinical Study ID

NCT02923752
46315
  • Ages > 18
  • All Genders

Study Summary

This is a new vessel wall imaging-based stroke registry which will investigate the clinical utility of the whole-brain intracranial vessel wall Magnetic Resonance Imaging (MRI) technique in assessing the etiologies in patients with ischemic stroke.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Male or female ≥ 18 years of age

  • Ischemic stroke onset within 8 weeks and confirmed by diffusion weighted MRI

  • Ability to read and understand informed consent

Exclusion

Exclusion Criteria:

  • The cause of stroke has been confirmed to be related to cardiac or extracranialcarotid or aorta pathologies.

  • Contraindications to MR imaging including mechanically, magnetically, or electricallyactivated implants, ferromagnetic implants and ferromagnetic foreign bodies,pregnancy.

  • Inability to tolerate MRI imaging secondary to an inability to lie supine or severeclaustrophobia.

  • Non-compliant with visit instructions, including inability to lie still, hold breathor follow procedure instructions

Study Design

Total Participants: 1000
Study Start date:
February 01, 2017
Estimated Completion Date:
August 01, 2019

Study Description

The registry will focus on investigating the utility of whole-brain vessel wall MRI techniques in assessing the etiologies in patients with recent ischemic stroke. Patients who have had ischemic stroke (as confirmed by diffusion weighted MRI) and have had or will undergo 3D whole-brain vessel wall MRI within 8 weeks of symptom onset will be recruited into this study. It is anticipated that a total of 1000 subjects will be recruited from Feb 2017 to Feb 2019. Approximately 12 centers in the US and China will participate in the registry. MRI whole-brain vessel wall images will be analyzed for detection and characteristics of various vessel wall pathologies and association between vessel wall imaging findings and patient's clinical information.

Connect with a study center

  • LiangXiang Hospital

    Beijiang, 100081
    China

    Active - Recruiting

  • Beijing AeroSpace Center Hospital

    Beijing, 100049
    China

    Active - Recruiting

  • Chaoyang Hospital, Capital Medical University

    Beijing, 100043
    China

    Active - Recruiting

  • Xuanwu Hospital, Capital Medical University

    Beijing, 100053
    China

    Active - Recruiting

  • West China Hospital, Sichuan University

    Chengdu, 610041
    China

    Active - Recruiting

  • Fujian Medical University Union Hospital

    Fuzhou, 350001
    China

    Active - Recruiting

  • Tianjin First Center Hospital

    Tianjin, 300192
    China

    Active - Recruiting

  • Tianjin Huanhu Hospital

    Tianjin, 300350
    China

    Active - Recruiting

  • The First Affiliated Hospital of Zhengzhou University

    ZhengZhou, 450052
    China

    Active - Recruiting

  • Cedars-Sinai Medical Center

    Los Angeles, California 90048
    United States

    Active - Recruiting

  • Keck Hospital of the University of Southern California

    Los Angeles, California 90033
    United States

    Site Not Available

  • Torrance Memorial Medical Center

    Torrance, California 90505
    United States

    Site Not Available

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