Effect of Hydrocortisone on Improving Outcome of Pneumatic Reduction of Infantile Intussusception

Last updated: August 25, 2024
Sponsor: Cairo University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Ileus

Treatment

Hydrocortisone

Saline

Clinical Study ID

NCT02691858
CAIUNIPEDSURG-CR3
  • Ages 3-4
  • All Genders

Study Summary

Intussusception is one of the most frequent causes of acute bowel and second most common cause of acute abdominal pain in pediatric age .95 % of cases are idiopathic, the rest are either due to pathological lead point or post operative. Treatment of intussusception must start with medical resuscitation, then radiological or operative reduction of intussusception.

Our surgery team has used hydrocortisone with the medical resuscitation to improve the success rate of pneumatic reduction and decrease the number of reduction trials.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Infantile Intussusception

Exclusion

Exclusion Criteria:

  • Peritonitis Pneumoperitoneum Morbid patients

Study Design

Total Participants: 80
Treatment Group(s): 2
Primary Treatment: Hydrocortisone
Phase:
Study Start date:
April 01, 2015
Estimated Completion Date:
December 31, 2025

Study Description

Experimental group will be given single dose IV Hydrocortisone 10 mg/kg with Resuscitation before attempting first trial of pneumatic reduction and the outcome measured.

Control group will be given Saline 100 ml IV single injection with Resuscitation before attempting first trial of pneumatic reduction and the outcome measured.

Connect with a study center

  • Cairo University Pediatric Hospital

    Cairo, 11432
    Egypt

    Active - Recruiting

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