Comparison of the Analgesic Effect of Different Local Anesthetics in Interscalene Nerve Block for Shoulder Surgery

Last updated: August 11, 2016
Sponsor: University Hospital, Antwerp
Overall Status: Completed

Phase

4

Condition

Neurologic Disorders

Treatment

N/A

Clinical Study ID

NCT02691442
EC 10/45/315
  • Ages 18-75
  • All Genders

Study Summary

Several reports have compared the duration of action of levobupivacaine and ropivacaine as local anesthetic. The most widely used method for sensory function evaluation is though means of a pinprick test. The investigators want to use the novel method of Quantitative Sensory Testing to better evaluate the anesthetic activity. This method used hot and cold sensation to assess small nerve fiber function. The investigators will assess the duration of action of different drugs when used in an inter scalene nerve block in patients scheduled for shoulder surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • American Society of Anesthesia class I or II

  • Scheduled for shoulder surgery

Exclusion

Exclusion Criteria:

  • Mental retardation

  • Allergy for local anesthetics

  • NSAID intolerance or contraindicated

  • Diabetes mellitus

  • Chronic use of pain killers

Study Design

Total Participants: 30
Study Start date:
December 01, 2010
Estimated Completion Date:
April 30, 2016

Study Description

This study aims to compare the length of the analgesic effect of different local anesthesic solutions, used in an interscalene nerve block. This will be objectified by measuring the changes in small nerve functioning, using quantative sensory testing. Based on the results of a previous study, the investigators reduce the dose of the administered local anesthetic, expecting a similar length of action using these smaller doses.