Lupus Intervention for Fatigue Trial

Last updated: April 3, 2025
Sponsor: Northwestern University
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Lupus

Pain (Pediatric)

Systemic Lupus Erythematosus

Treatment

Control

Experimental

Clinical Study ID

NCT02653287
LIFT Study
  • Ages 18-80
  • All Genders

Study Summary

Participants in the Chicago Lupus Database or individuals seen at Northwestern Medicine will be approached to enroll in a one year clinical trial looking at decreasing fatigue in persons with systemic lupus erythematosus (SLE). The intervention group will receive individual coaching sessions focusing on physical activity and nutrition while the control group will receive individual calls in relation to SLE self-management educational sessions.This study is designed to evaluate the LIFT intervention to decrease fatigue (primary outcome), improve physical activity (secondary outcome) and dietary behavior (exploratory outcome) in persons with SLE.

Eligibility Criteria

Inclusion

Inclusion criteria:

  • include meeting at least 4 of 11 American College of Rheumatology (ACR)classification criteria for definite SLE, or 3 out of 11 ACR classification criteriawith also meeting at least one SLICC criteria

  • be at least 18 years of age

  • have a BMI between 18-40 kg/m2

  • be able to ambulate at least household distances (50ft)

  • be able to provide informed consent.

  • be able to speak and read English

Exclusion

Exclusion criteria:

  • include pregnancy at baseline

  • not meeting inclusion criteria.

Study Design

Total Participants: 200
Treatment Group(s): 2
Primary Treatment: Control
Phase:
Study Start date:
May 01, 2019
Estimated Completion Date:
December 31, 2025

Study Description

Participants in the Chicago Lupus Database or individuals seen at Northwestern Medicine will be approached to enroll in a one year clinical trial looking at decreasing fatigue in persons with systemic lupus erythematosus (SLE). The intervention group will receive individual coaching based in motivational interviewing sessions focusing on physical activity and nutrition while the control group will receive individual calls focusing on SLE self-management. This study is designed to evaluate the LIFT intervention to decreased fatigue (primary outcome), improve physical activity (secondary outcome) and dietary behavior (exploratory outcome) in persons with SLE.

Connect with a study center

  • Holly Milaeger

    Chicago, Illinois 60611
    United States

    Site Not Available

  • Northwestern University

    Chicago, Illinois 60611
    United States

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.