Phase
Condition
Alzheimer's Disease
Memory Problems
Dementia
Treatment
sham
RTMS
Clinical Study ID
Ages 55-99 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Veterans aged 55 years or older
Diagnosed with Mild Cognitive Impairment (MCI) or dementia likely due to Alzheimer'sdisease.
Ability to obtain a Motor Threshold, determined during the screening process.
With an adequately stable condition and living environment to enable attendance atscheduled clinic visits.
If on a prescription medication for cognition that medication dose will be stablefor at least 4 weeks prior to randomization into the study and participant will bewilling to remain on a stable regimen during the acute treatment phase.
Able to read, verbalize understanding, and voluntarily sign the Informed ConsentForm to be signed by the participant, or a designated legal representative when theparticipant lacks decision making capacity prior to participating in any study-specific procedures or assessments.
Exclusion
Exclusion Criteria:
Patients with prior exposure to rTMS or electroconvulsive therapy (ECT).
Unable to safely withdraw, at least two weeks prior to treatment commencement, frommedications that substantially increase the risk of having seizures.
Have a cardiac pacemaker or a cochlear implant.
Have an implanted device deep brain stimulation or metal in the brain
Current substance abuse not including caffeine or nicotine as determined by patientreport or chart review.
Active current suicidal intent or plan as determined by patient report or chartreview.
Current or Prior history of a seizure disorder as determined by patient report orchart review
Traumatic brain injury within the last two months
Participation in another concurrent interventional clinical trial
Known current psychosis as determined by patient report or chart review.
Current or prior history of a mass lesion, cerebral infarct or other non-cognitive,active central nervous system (CNS) disease that would increase the risk forseizure.
Not fluent in English or a hearing impairment severe enough to impair comprehension
Study Design
Study Description
Connect with a study center
VA Palo Alto Health Care System, Palo Alto, CA
Palo Alto, California 94304-1207
United StatesSite Not Available
VA Palo Alto Health Care System, Palo Alto, CA
Palo Alto 5380748, California 5332921 94304-1207
United StatesSite Not Available

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