Huaier Granule in Treating Women With Triple Negative Breast Cancer

Inclusion Criteria:

• Age: ≥ 18 and ≤ 75 years, female;

• Triple negative breast cancer has been surgically removed;

• The triple negative breast cancer has been confirmed by pathological examination andImmunohistochemistry (IHC);

• Not receiving any preoperative anticancer drugs;

• The liver and kidney function satisfies the following conditions within 3 days aftersurgery (excluding day 3): aspartate aminotransferase (AST), glutamic-oxalacetictransaminase (ALT) < 2 upper limit of normal (ULN), total bilirubin ≤ 1.5 ULN, serumcreatinine < 1.5 ULN;

• Other laboratory tests meet the following requirements within 3 days after surgery (excluding day 3): Hb ≥ 90g/l, platelet count ≥ 100×109/L, absolute neutrophil count > 1.5×109/L;

• The expected survival time ≥ 6 months;

• The subjects volunteer to sign the informed consent.

Exclusion Criteria:

• Patients with stage IV breast cancer;

• Triple negative breast cancer was not surgically removed;

• Non-triple negative breast cancer patients confirmed by pathological examination andImmunohistochemistry (IHC);

• Pregnant or lactating women;

• Those with active bleeding due to various reasons;

• Those with HIV infection or AIDS-associated diseases;

• Those with severe acute and chronic diseases;

• Those with severe diabetes;

• Those with serious infectious diseases;

• Those who can not take drugs by oral route;

• Drug abusers or those with psychological or mental diseases that may interfere withstudy compliance;

• Conditions that are considered not suitable for this study investigators