Minto Model in Effect Site Mode for Target-Controlled Infusion of Remifentanil During Cardiopulmonary Bypass

Last updated: October 18, 2016
Sponsor: Seoul National University Hospital
Overall Status: Completed

Phase

4

Condition

Drugs

Anesthesia

Treatment

N/A

Clinical Study ID

NCT02566733
Remifentanil_CPB
  • Ages 20-80
  • All Genders

Study Summary

Target controlled infusion with remifentanil is widely used during cardiac surgery, wich is performed using the Minto model. It was derived from patients undergoing general surgery. However, pharmacokinetics of remifentanil can be changed during cardiopulmonary bypass. The investigators tested whether Minto model for target controlled infusion produces constant plasma remifentanil concentration during the cardiac surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult patients with the ASA class I~III undergoing elective cardiac surgery usingcardiopulmonary bypass

Exclusion

Exclusion Criteria:

  • Patients not using target controlled infusion during the operation

  • Patients with drug/substance abuse

  • Patients using analgesics before this study starts

  • Pregnant women

  • Patients who rejected study participation

Study Design

Total Participants: 56
Study Start date:
October 01, 2015
Estimated Completion Date:
June 30, 2016

Connect with a study center

  • Seoul National University Hospital

    Seoul, 03080
    Korea, Republic of

    Site Not Available

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