Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine Consumption

Last updated: April 27, 2017
Sponsor: Pia Jaeger
Overall Status: Completed

Phase

4

Condition

Pain

Acute Pain

Chronic Pain

Treatment

N/A

Clinical Study ID

NCT02539628
SM3-PJ-14
2014-005642-22
  • Ages > 18
  • All Genders

Study Summary

The investigators believe sufficient spread to all nerves within the adductor canal—and thereby sufficient analgesia—can only be obtained by bolus injections and not by continuous infusions via a catheter. The aim of the study is to investigate whether an adductor canal block performed as repeated intermittent boluses provides superior pain relief to continuous infusion. The investigators hypothesize that adductor canal block performed as intermittent boluses via a catheter will reduce morphine consumption and pain as well as enhance ambulation and muscle strength compared with continuous infusion.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients scheduled for total knee arthroplasty in spinal anesthesia

  • Patients who gave their written informed consent to participating in the study afterhaving fully understood the contents of the protocol and restrictions

  • American society of anesthesiologists 1-3

  • Ability to perform a timed up and go test preoperatively

Exclusion

Exclusion Criteria:

  • Patients who cannot cooperate

  • Patients who cannot understand or speak Danish.

  • Patients with allergy to the medicines used in the study

  • Patients with a daily intake of strong opioids (morphine, oxycodone, ketobemidone,methadone, fentanyl) during the last 4 weeks

  • Patients suffering from alcohol and/or drug abuse - based on the investigator'sassessment

  • Rheumatoid arthritis

  • BMI > 40

  • Neuromuscular pathology in the lower limbs

  • Pregnancy

Study Design

Total Participants: 110
Study Start date:
March 01, 2015
Estimated Completion Date:
September 30, 2016

Connect with a study center

  • Department of Anaesthesia-Surgery-Intensive Care, Gentofte Hospital

    Gentofte, Hellerup 2900
    Denmark

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.