Last updated: March 28, 2023
Sponsor: Beijing Tiantan Hospital
Overall Status: Completed
Phase
2
Condition
Thrombosis
Stroke
Blood Clots
Treatment
N/AClinical Study ID
NCT02526225
1412-Z-YXET-ZS-RE
Ages 18-80 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Aged 18 to 80 years of age, and gender not limited。
- Within 48 hours of stroke onset of ischemic stroke (diagnosis standard by the Chinesemedical association of the fourth national conference on cerebrovascular disease);
- The first onset, or always not obvious legacy of stroke sequela (mRS acuities werebefore the onset of 1);
- The degree of nerve function defect score (NIHSS) score 4 to 24 points, body movementcomponent (NIHSS score paragraphs 5 and 6) total score 2 points or higher;
- Understand and voluntarily signed informed consent.
Exclusion
Exclusion Criteria:
- Head imaging studies have confirmed that, encephalitis, brain tumor, brain abscess andcause similar symptoms of disease, or confirm with hemorrhagic cerebral infarction,epidural hematoma, intracranial hematoma, intraventricular hemorrhage, subarachnoidhemorrhage, etc.
- The serious disturbance of consciousness (Ia NIHSS score 2 points or higher);
- With hemorrhagic disease or have a bleeding tendency, or have a lower limb venousthrombosis;
- Serious abnormal liver and kidney function, liver function laboratory indexes of ALT > 3 ULN, renal laboratory ULN Cr > 1.5);
- A history of mental illness or dementia patients;
- Severe organ or other systemic disease, accompanied by any organ or system ofmalignant tumor, or ongoing anti-tumor treatment, the estimated lifetime < 3 months;
- Significant drug or alcohol abuse;
- Allergic constitution, as well as to two or more drugs or food allergies;This medicineingredients allergy or known;
- Have pregnancy (check blood HCG positive screening tests, namely HCG > 5 miu/mL),during the test preparation is pregnancy or lactation in women;
- In the past three months in other clinical trials;
- Researchers do not determine poor adherence, or any other suitable for patients toparticipate in this study.
Study Design
Total Participants: 3452
Study Start date:
February 01, 2016
Estimated Completion Date:
August 31, 2019
Study Description
Connect with a study center
Tiantan Hospital
Beijing, Beijing 100050
ChinaSite Not Available

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