Effects of 10 mg Monacolins on Vascular Health: a Clinical Trial

Last updated: January 30, 2024
Sponsor: University of Bologna
Overall Status: Completed

Phase

N/A

Condition

Atherosclerosis

Treatment

Red yeast rice

Placebo

Clinical Study ID

NCT02492464
Monasc10_15
  • Ages 18-70
  • All Genders

Study Summary

This will be a double-blind randomized clinical trial carried out on subjects with suboptimal control of LDL-cholesterolemia, following a Mediterranean diet, and treated with a red yeast rice extract (containing 10 mg monacolin K per daily dose) or placebo, in order to evaluate the middle-term effects on vascular health evaluated by non invasive methods (Vicorder(R) apparatus)

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • LDL-cholesterol between 130 and 190 mg/dL

Exclusion

Exclusion Criteria:

  • Secundary prevention for cardiovascular disease
  • Type 2 diabetes
  • Assumption of lipid-lowering drug or dietary supplements
  • Previous intolerans to read yeast rice including dietary supplements

Study Design

Total Participants: 40
Treatment Group(s): 2
Primary Treatment: Red yeast rice
Phase:
Study Start date:
May 01, 2015
Estimated Completion Date:
December 31, 2015

Connect with a study center

  • S. Orsola-Malpighi University Hospital

    Bologna, BO 40138
    Italy

    Site Not Available

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