International HIT-MED Registry (I-HIT-MED)

The following patients can be included in this registry:

Children and adults with

• Medulloblastoma (MB)

• Ependymoma

• Pineal Tumours

• Chroroid plexus tumours

Objectives of this registry:

To prospectively evaluate the clinical courses of patients with the eligible brain tumours, considering neuroradiological, pathological, and molecular / biological characteristics of the tumour and individual standard treatment data.

To collect biological specimens (tumour, CSF, peripheral blood) or their data to perform biological studies on

• disease aetiology

• molecular / biological risk factors influencing treatment response and survival

• potential targets for drug treatment in future patients

To assess the use of systems for quality assurance during diagnosis and treatment of brain tumours.

To assess long-term follow-up, quality of survival, neuropsychology, and other patient-centred research in these very rare tumour subtypes in the context of the registry or in cooperation with external collaborators.