Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus

Last updated: September 25, 2016
Sponsor: Cairo University
Overall Status: Completed

Phase

3

Condition

Warts

Rash

Treatment

N/A

Clinical Study ID

NCT02329600
polyphenol_TOC_OLP
  • Ages 30-68
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The study included forty individuals divided into 3 groups. 10 control subjects, 15 oral lichen planus (OLP) patients who were treated with topical corticosteroids and 15 oral lichen planus (OLP) patients who were treated with topical corticosteroids and green tea tablets.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients presented with painful oral lichen planus lesions

  • Free of any visible oral lesions other than oral lichen planus

  • Free of any systemic diseases

Exclusion

Exclusion Criteria:

  • Topical treatment or systemic therapy of OLP for one month before starting the study

  • Pregnant or breast feeding women

  • Smokers

  • Use of corticosteroids or other immunosuppressive drugs

Study Design

Total Participants: 40
Study Start date:
June 01, 2013
Estimated Completion Date:
October 31, 2014

Study Description

This study included forty individuals divided into 3 groups. Group A; 10 systemically healthy control subjects not receiving medication.

Group B; 15 Patients who were previously diagnosed with OLP presented in acute exacerbation were treated with topical corticosteroids; Triamcinolone acetonide (Kenalog in orabase: Bristol-Myers, Squibb, Spain) applied topically 4 times a day i.e. following each meal and at bed time for one month.

Group C; 15 Patients who were previously diagnosed with OLP presented in acute exacerbation were treated with both topical corticosteroids; Triamcinolone acetonide (Kenalog in orabase: Bristol-Myers, Squibb, Spain) applied topically 4 times a day i.e. following each meal and at bed time for one month in addition to green tea tablets 200 mg (Green tea extract 5:1, El Obour For Modern Pharmaceutical Industries) as one tablet a day also for one month.