Effects of Pectin Supplementation in Diarrhea-predominant Irritable Bowel Syndrome

Last updated: March 23, 2016
Sponsor: Nanjing PLA General Hospital
Overall Status: Completed

Phase

3

Condition

Lactose Intolerance

Hyponatremia

Gastrointestinal Diseases And Disorders

Treatment

N/A

Clinical Study ID

NCT02270268
2011NLY073
  • Ages 18-70
  • All Genders

Study Summary

The purpose of this study is to investigate the effect of pectin, a kind of soluble dietary fiber, on clinical symptoms, gut microbiota and the immune status in patients with diarrhea-predominant irritable bowel syndrome

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • All patients(age≧18y)

  • Admitted for diarrhea-predominant irritable bowel syndrome

Exclusion

Exclusion Criteria:

  • Mental disorders

  • Cancer

  • Inflammatory bowel disease

Study Design

Total Participants: 114
Study Start date:
November 01, 2011
Estimated Completion Date:
October 31, 2013

Study Description

Patients were randomized to receive either pectin or placebo. Treatment consisted of 6 weeks supplementation with pectin (fiber group) or placebo (maltodextrin). We evaluated the clinical symptoms, gut microbiota and the immune markers in two groups.