Prediction of Fluid Responsiveness in Atrial Fibrillation Patients Who Underwent Valvular Heart Surgery: Peep-induced Increase in Central Venous Pressure vs. Passive Leg Raising

Last updated: March 31, 2015
Sponsor: Yonsei University
Overall Status: Completed

Phase

N/A

Condition

Arrhythmia

Cardiac Disease

Chest Pain

Treatment

N/A

Clinical Study ID

NCT02224378
4-2011-0686
  • Ages > 20
  • All Genders

Study Summary

Dynamic indices of preload depending on the heart-lung interaction require sinus rhythm and cannot be applied to patients with atrial fibrillation. PEEP-induced increase in central venous pressure (CVP) was shown to be a valid predictor of fluid responsiveness after cardiac surgery in patients with sinus rhythm, and was speculated to be of value in patients with rhythm other than sinus. The aim of this study is to assess the predictability of PEEP-induced increase in CVP and passive leg raising (PLR)-induced changes in stroke volume index (SVI) on fluid responsiveness in patients with atrial fibrillation following valvular heart surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. age ≥20

  2. atrial fibrillation patients who underwent elective valvular heart surgery

Exclusion

Exclusion Criteria:

  1. age < 20

  2. LV ejection fraction < 40%

  3. any pulmonary disease

  4. end stage renal disease

  5. high intrabdominal pressure patient

  6. contraindication of passive leg raising

  7. deep vein thrombosis

Study Design

Total Participants: 44
Study Start date:
March 01, 2012
Estimated Completion Date:
October 31, 2014

Connect with a study center

  • Department of Anesthesiology & Pain Medicine, Yonsei university college of medicine

    Seoul, 120-752
    Korea, Republic of

    Site Not Available

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