Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain

Phase

Condition

Peripheral Neuropathy

Pain

Pain (Pediatric)

Treatment

N/A

Clinical Study ID

NCT02217267

SI140/2014

Ages 18-75
All Genders
Accepts Healthy Volunteers

Study Summary

The purpose of this study to evaluated Long term outcome after serial Lidocaine infusion when compared with placebo in peripheral neuropathic pain patients in acute stage (less than 6 months) at 3 months after first time of infusion

Eligibility Criteria

Inclusion

Inclusion Criteria:

Peripheral neuropathic pain from peripheral nerve injury within 6 months after injury
Well understand to Thai language in writing or listening

Exclusion

Exclusion Criteria:

Underlying Heart disease or Arrhythmia
Allergy to lidocaine, Gabapentin, Carbamazepine, tramadol
History of epilepsy
History of lidocaine used
Underlying Psychiatric disease
History of drug abuse
Pregnancy and nursing

Study Design

August 01, 2014

February 28, 2018

Study Description

Peripheral nerve injury may give rise to severe and long-lasting types of pains which are often resistant to treatment such as opioid, tricyclic antidepressant or anticonvulsant. Lidocaine infusion has been the one of intractable neuropathic pain treatment . My hypothesis the serial lidocaine infusion can adequate pain control and can prevent chronic pain (central sensitisation). Therefore, we designed this prospective, randomised, double-blind, controlled study to evaluate the efficacy of serial lidocaine infusion in peripheral neuropathic pain compared with placebo in long term outcome (at 3 month).

Connect with a study center

Faculty of medicine Siriraj Hospital Mahidol University
Bangkoknoi, Bangkok 10700
Thailand
Site Not Available

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