Screening for Early Lung Cancer in Shanghai, China

Last updated: December 16, 2014
Sponsor: Shanghai Changzheng Hospital
Overall Status: Trial Status Unknown

Phase

2

Condition

Non-small Cell Lung Cancer

Lung Cancer

Lung Disease

Treatment

N/A

Clinical Study ID

NCT02185495
13411950100
  • Ages 35-74
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Imaging procedures including chest X-ray and low-dose computed tomography may be effective in lung cancer early detection. Yet it is unknown whether low-dose computed tomography combined with computer aided detection （CAD) is more effective than LDCT in screening of early lung cancer.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age of 55 to 74 years; smoking history of at least 30 pack-years; and if formersmoker, have quit within 15 years

  • Age 50 or older ,20 or more pack-year history of smoking, and one additional riskfactor (occupational exposure, residential radon exposure, cancer history, familyhistory of lung cancer, history of lung disease)

  • Age 35 and one additional risk factor

  • Ability to accept LDCT examination and sign informed consent form

Exclusion

Exclusion Criteria:

  • Individuals with any symptoms suggestive of lung cancer （e.g., vigorous coughing,chest pain, weight loss, blood-stained sputum）

  • Individuals with acute pulmonary abnormalities or those in poor health conditions orthose have metallic implants or devices in the chest or back will be excluded due tothe potential impact on the results as well as difficulty of acquiring the images.

  • Pregnant women

Study Design

Total Participants: 3000
Study Start date:
July 01, 2014
Estimated Completion Date:
September 30, 2017

Study Description

The randomized clinical trial is to investigate and compare the effectiveness of CAD-guided low-dose computed tomography and low-dose computed tomography in lung cancer screening for community individuals in Shanghai, China. Thus, an imaging protocol which can detect early lung cancer in asymptomatic high risk patients will be proposed.

Connect with a study center

  • Changzheng Hospital

    Shanghai, Shanghai 200003
    China

    Active - Recruiting

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.