Acetyl-L-Carnitine Reduces Perceived Work Stress and Improves Work Ability and Work Performance in Hepatic Encephalopathy

Last updated: June 23, 2014
Sponsor: University of Catania
Overall Status: Completed

Phase

3

Condition

Hepatic Encephalopathy

Arginase Deficiency

Vomiting

Treatment

N/A

Clinical Study ID

NCT02173132
1/2010
  • Ages 33-68
  • All Genders

Study Summary

This study evaluated the effects of acetyl-L-carnitine treatment on Perceived Work Stress, Work Ability and Work Performance in subjects with Hepatic Encephalopathy.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • overt hepatic encephalopathy (HE) or a history of overt HE

Exclusion

Exclusion Criteria:

  • history of recent alcohol intake; infection; recent antibiotic use or gastrointestinalbleeding; history of recent use of drugs affecting psychometric performances likebenzodiazepines, antiepileptics or psychotropic drugs; a history of shunt surgery ortransjugular intrahepatic portosystemic shunt for portal hypertension; electrolyteimbalance; renal impairment; hepatocellular carcinoma; severe medical problems such ascongestive heart failure, pulmonary disease or neurological or psychiatric disorderthat could influence quality of life measurement; inability to performneuropsycological tests.

Study Design

Total Participants: 94
Study Start date:
April 01, 2010
Estimated Completion Date:

Connect with a study center

  • University of Catania

    Catania, 95126
    Italy

    Site Not Available

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