Phase
Condition
Sjogren's Syndrome
Eyelid Inflammation
Dry Eyes
Treatment
N/AClinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Greater than or equal to 2 of the following 4 signs in the same eye at screening andbaseline visits (Same signs must be present at Screening and Baseline visits):Conjunctival staining present greater than or equal to 1 (out of possible score of 6per eye), Corneal fluorescein staining present greater than or equal to 4 (out of apossible score of 15 per eye), Tear film break up time (TBUT) less than or equal to 7seconds, Schirmer's test greater than or equal to 1 to less than or equal to 7 mm in 5minutes.
- Ocular Surface Disease Index (OSDI) score: 25-80 at screening, 21-80 at baseline.
- Symptoms of DED for greater than or equal to 6 months.
- Use of or desire to use artificial tears at least 2 times per day in preceding 2weeks.
- Ability to swallow large, soft gelcaps
Exclusion
Exclusion Criteria:
- Allergic to ingredients in supplements or placebo
- Contact lens wear
- Pregnant, nursing, or lactating
- Current ocular infection, inflammation, or acute allergic conjunctivitis
- History of: ocular herpetic keratitis, ocular surgery in past 6 months, LASIK surgery,use of glaucoma medicine or surgery for glaucoma, liver disease, atrial fibrillation,hemophilia or bleeding tendencies
- Currently on anticoagulation therapy
- Eyelid abnormalities or extensive ocular scarring
- Use of EPA/DHA supplements in excess of 1200 mg per dayi
- Current use, insufficient washout period, or intent to change specific treatments fordry eye disease
Study Design
Study Description
Connect with a study center
Mayo Clinic Arizona
Scottsdale, Arizona 85259
United StatesSite Not Available
Stephen Cohen, OD PC
Scottsdale, Arizona 85254
United StatesSite Not Available
Milton M. Hom, OD, FAAO
Azusa, California 91702
United StatesSite Not Available
University of California, Berkeley
Berkeley, California 94720
United StatesSite Not Available
Pendleton Eye Center
Oceanside, California 92056
United StatesSite Not Available
Wolstan and Goldberg Eye Associates
Torrance, California 90505
United StatesSite Not Available
Peter C. Donshik, MD, PC
Bloomfield, Connecticut 06002
United StatesSite Not Available
Shettle Eye Research
Largo, Florida
United StatesSite Not Available
Eye Care Centers Management, Inc.
Morrow, Georgia 30260
United StatesSite Not Available
University of Illinois Hospital & Health Sciences
Chicago, Illinois 60612
United StatesSite Not Available
Price Vision Group
Indianapolis, Indiana 46260
United StatesSite Not Available
KU Eye Center
Prairie Village, Kansas 66208
United StatesSite Not Available
Massachusetts Eye and Ear Infirmary
Boston, Massachusetts 02114
United StatesSite Not Available
Tufts Medical Center
Boston, Massachusetts 02111
United StatesSite Not Available
Clinical Eye Research of Boston
Winchester, Massachusetts 01890
United StatesSite Not Available
University of Michigan Kellogg Eye Center
Ann Arbor, Michigan 48105
United StatesSite Not Available
Minnesota Eye Consultants, P.A.
Bloomington, Minnesota 55431
United StatesSite Not Available
Mulqueeny Eye Centers
Creve Coeur, Missouri 63141
United StatesSite Not Available
Silverstein Eye Centers
Kansas City, Missouri 64133
United StatesSite Not Available
Tauber Eye Center
Kansas City, Missouri 64111
United StatesSite Not Available
Icahn School of Medicine at Mount Sinai
New York, New York 10029
United StatesSite Not Available
Universtity of Rochester-Flaum Eye Institute
Rochester, New York 14642
United StatesSite Not Available
South Shore Eye Care, LLP
Wantagh, New York 11793
United StatesSite Not Available
Ophthalmic Consultants of Long Island
Westbury, New York 11590
United StatesSite Not Available
Oculus Research at Garner at Eyecarecenter
Raleigh, North Carolina 27603
United StatesSite Not Available
Case Western Reserve University
Cleveland, Ohio 44106
United StatesSite Not Available
Northeast Ohio Eye Surgeons
Kent, Ohio 44240
United StatesSite Not Available
Scheie Eye Institute, University of Pennsylvania
Philadelphia, Pennsylvania 19104
United StatesSite Not Available
Southern College of Optometry
Memphis, Tennessee 38104
United StatesSite Not Available
The Eye Centers of Racine and Kenosha
Racine, Wisconsin 53405
United StatesSite Not Available
Not the study for you?
Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.