Germ Cell Tumor and Testicular Tumor DNA Registry

Last updated: July 3, 2024
Sponsor: Memorial Sloan Kettering Cancer Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Genitourinary Cancer

Brain Tumor

Neoplasms

Treatment

sample of blood or saliva

Questionnaires

Clinical Study ID

NCT02099734
14-016
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without these tumors. This study will help us learn more about the prevention, diagnosis, treatment and outcome of these tumors. Studying relatives of patients and people unrelated to patients with GCT and other testicular tumors will help us understand why some people get these tumors and why some people don't.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Case Cohort

  • Must be ≥ 18 years of age AND

  • Must be an English-speaker AND

  • Must have a diagnosis or suspicion of germ cell tumor and/or a testicular mass

Family Member Cohort

  • Must be ≥ 18 years of age AND

  • Must be an English-speaker AND

  • Must be a blood relative of the proband. Family members of probands are eligible.These individuals need not have a diagnosis of GCT-TT, as they will be used forsegregation analysis of suspected variants found in the proband.

Control Cohort

  • Must be ≥ 18 years of age AND

  • Must be an English-speaker AND

  • Must not have a personal history of cancer, with the exception of non-melanoma skincancer, AND

  • Must not have a family history of germ cell tumor or testicular tumor AND

  • Must not be a blood relative of controls enrolled in this study

Exclusion

Exclusion Criteria:

Study Design

Total Participants: 1000
Treatment Group(s): 2
Primary Treatment: sample of blood or saliva
Phase:
Study Start date:
January 01, 2014
Estimated Completion Date:
January 31, 2026

Connect with a study center

  • Memoral Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey 07748
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey 07645
    United States

    Active - Recruiting

  • Cold Springs Harbor Laboratory (Specimen Analysis)

    Cold Spring Harbor, New York 11724
    United States

    Site Not Available

  • Memorial Sloan Kettering Commack

    Commack, New York 11725
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Westchester

    Harrison, New York 10604
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Cancer Center

    New York, New York 10065
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Rockville Centre

    Rockville Centre, New York 11570
    United States

    Site Not Available

  • Memoral Sloan Kettering Cancer Center at Phelps

    Sleepy Hollow, New York 10591
    United States

    Site Not Available

  • Memorial Sloan Kettering Nassau

    Uniondale, New York 11553
    United States

    Site Not Available

  • Memorial Sloan Kettering Westchester

    West Harrison, New York 10604
    United States

    Site Not Available

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