Efficacy and Safety of Shenyankangfu Tablets for Primary Glomerulonephritis

Last updated: June 29, 2015
Sponsor: Chinese PLA General Hospital
Overall Status: Trial Status Unknown

Phase

4

Condition

Glomerulonephritis

Proteinuria

Treatment

N/A

Clinical Study ID

NCT02063100
S2013-055-03
  • Ages 18-70
  • All Genders

Study Summary

-Evaluate the efficacy and safety of Shenyankangfu Tablets to control the proteinuria of patients with primary glomerulonephritis compare with Losartan potassium.

Eligibility Criteria

Inclusion

Inclusion

  • Diagnosed with primary glomerulonephritis

  • Aged from 18 to 70 years,male or female

  • Blood pressure can be controlled ≤140/90mmHg

  • GFR≥45ml/min/1.73㎡

  • 0.5g≤24 hours proteinuria≤3.0g

  • Traditional Chinese medicine syndrome conform Qi-Yin Deficiency

  • Obtain the agreement of patients or their guardians, and signed informed consent file

Exclusion

Exclusion Criteria:

  • secondary nephropathy

  • Take the glucocorticoid,immunosuppressants and Tripterygium drug in the last 12 months

  • Take other Chinese patent medicine and decoction which can reduce proteinuria in thelast 2 weeks

  • Take renin-angiotensin system blockers in last 4 weeks

  • Combined with severe primary disease of heart, brain, liver and hematopoietic system,or other serious diseases can affect patient's life

  • Pregnant or lactating women

  • Allergic predisposition or known to be allergic to the drug composition

  • Blood presser <90/60mmHg

  • With unilateral or bilateral renal artery stenosis

  • With mental disorders and poor compliance

  • Be suspected or confirmed with alcohol, drug abuse history

  • Be participating in another clinical study at the same period

Study Design

Total Participants: 720
Study Start date:
February 01, 2014
Estimated Completion Date:

Connect with a study center

  • Beijing Friendship,Capital Medical University

    Beijing, Beijing
    China

    Active - Recruiting

  • Guang'anmen Hospital, China Academy of Chinese Medical Sciences

    Beijing, Beijing
    China

    Active - Recruiting

  • National Clinical Research Center for Kidney Disease, State Key Laboratory of Kidney Disease, Department of Nephrology, Chinese PLA General Hospital

    Beijing, Beijing 100853
    China

    Active - Recruiting

  • XIyuan Hospital CACMS

    Beijing, Beijing
    China

    Site Not Available

  • Daping Hospital,Research Institute of Surgery Third Military Medical University

    Chongqing, Chongqing
    China

    Active - Recruiting

  • Fuzhou General Hospital Nanjing Military Command

    Fuzhou, Fujian
    China

    Active - Recruiting

  • 174th hospital of the People's Liberation Army

    Xiamen, Fujian
    China

    Active - Recruiting

  • Guangdong Province Hospital of Chinese Medical

    Guangzhou, Guangdong
    China

    Active - Recruiting

  • Guangzhou First People's Hospital

    Guangzhou, Guangdong
    China

    Active - Recruiting

  • Beidaihe Sanatorium of Beijing Military Mrca

    Qinhuangdao, Hebei
    China

    Active - Recruiting

  • The Third Hospital of hebei Medical University

    Shijiazhuang, Hebei
    China

    Active - Recruiting

  • Heilongjiang University of Chinese Medicine

    Harbin, Heilongjiang
    China

    Active - Recruiting

  • Henan Provincial People'S Hospital

    Zhengzhou, Henan
    China

    Active - Recruiting

  • The Second Xiangya Hospital of Central South University

    Changsha, Hunan
    China

    Site Not Available

  • The Third Xiangya Hospital of Central South University

    Changsha, Hunan
    China

    Active - Recruiting

  • Xiangya Hospital Central South University

    Changsha, Hunan
    China

    Active - Recruiting

  • Jiangsu Province Hospital

    Nanjing, Jiangsu
    China

    Active - Recruiting

  • Jiangxi Provincil People'S Hospital

    Nanchang, Jiangxi
    China

    Active - Recruiting

  • The Second Hospital of Jilin University

    Changchun, Jilin
    China

    Active - Recruiting

  • First Affilated Hospital of Dalian Medical University

    Dalian, Liaoning
    China

    Active - Recruiting

  • Shaanxi Traditional Chinese Medicine Hospital

    Xi'an, Shaanxi
    China

    Active - Recruiting

  • Tangdu Hospital

    Xi'an, Shaanxi
    China

    Active - Recruiting

  • The First Affiliated Hospital of Xi'An Jiaotong University

    Xi'an, Shaanxi
    China

    Active - Recruiting

  • Xijing Hospital

    Xi'an, Shaanxi
    China

    Active - Recruiting

  • Shandong Province Hospital

    Jinan, Shandong
    China

    Active - Recruiting

  • Teaching Hospital of Shandong University of Traditional Chinese Medicine

    Jinan, Shandong
    China

    Active - Recruiting

  • Changhai Hospital of Shanghai

    Shanghai, Shanghai
    China

    Active - Recruiting

  • LONGHUA Hospital Shanghai University of TCM

    Shanghai, Shanghai
    China

    Active - Recruiting

  • Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai
    China

    Active - Recruiting

  • Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University

    Shanghai, Shanghai
    China

    Active - Recruiting

  • Shugaung Hospital

    Shanghai, Shanghai
    China

    Active - Recruiting

  • Xin Hua Hospital Affiated to Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai
    China

    Active - Recruiting

  • First Hospital of Shanxi Medical University

    Taiyuan, Shanxi
    China

    Active - Recruiting

  • Second Hospital of Shanxi Medical University

    Taiyuan, Shanxi
    China

    Active - Recruiting

  • Shanxi Hospital of Integrated Traditional and Westem Medicine

    Taiyuan, Shanxi
    China

    Active - Recruiting

  • Shanxi Provincial People's Hospital

    Taiyuan, Shanxi
    China

    Active - Recruiting

  • General Hospital of Chengdu Military Region of PLA

    Chengdu, Sichuan
    China

    Active - Recruiting

  • Teaching Hospital of Chengdu University of T.C.M

    Chengdu, Sichuan
    China

    Active - Recruiting

  • First Teaching Hospital of Tianjin University of TCM

    Tianjin, Tianjin
    China

    Active - Recruiting

  • Tianjin Medical University General Hospital

    Tianjin, Tianjin
    China

    Active - Recruiting

  • Hangzhou Hospital of Traditional Chinese Medicine

    Hangzhou, Zhejiang
    China

    Active - Recruiting

  • Tongde Hospital of Zhejiang Province

    Hangzhou, Zhejiang
    China

    Active - Recruiting

  • Zhejiang Provncial People'S Hospital

    Hangzhou, Zhejiang
    China

    Active - Recruiting

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