Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery

Last updated: April 28, 2017
Sponsor: Beth Israel Medical Center
Overall Status: Completed

Phase

3

Condition

Post-surgical Pain

Chronic Pain

Pain

Treatment

N/A

Clinical Study ID

NCT01983020
IRB 073-10
  • Ages > 18
  • All Genders

Study Summary

This study has been designed as a controlled clinical trial to evaluate the efficacy of brief lidocaine infusion, brief ketamine infusion and a lidocaine/ketamine combined infusion when added to conventional opioid therapy following major spine surgery, as well as to evaluate the effects of the lidocaine/ketamine pain protocol on the feasibility of performing routine intraoperative neurophysiology during spine surgery in adults and determine whether this infusion protocol is compatible with intraoperative neurophysiology on spine surgery patients. If one or more of the approaches is confirmed as efficacious and safe, it could have a significant impact on the routine management of postoperative pain in this context.

Eligibility Criteria

Inclusion

Inclusion Criteria: Male and Female >/= 18 years of age Patients undergoing first-time fusion surgery orsurgery to revise a prior fusion Able to read, write and speak in English, and able to giveinformed consent for the study

Exclusion

Exclusion Criteria: Any disease associated with major organ dysfunction renal dysfunction hepatic dysfunctioncardiac dysfunction

Study Design

Total Participants: 46
Study Start date:
April 01, 2011
Estimated Completion Date:
January 31, 2013

Connect with a study center

  • Beth Israel Medical Center

    New York, New York 10003
    United States

    Site Not Available

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