Dexamethasone-induced Hiccup in Chemotherapy Patients Treated by Methylprednisolone Rotation

Last updated: April 27, 2017
Sponsor: Chung-Ang University
Overall Status: Completed

Phase

3

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT01974024
GSNUH 2013-1
  • Ages > 18
  • All Genders

Study Summary

The aims of this study were to investigate the feasibility of methylprednisolone rotation as treatment of DIH.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • all solid cancer patients on chemotherapy

  • age >18 years

  • received dexamethasone as an antiemetic

Exclusion

Exclusion Criteria:

  • brain metastases

  • hiccups before dexamethasone administration

  • uncontrolled diabetes mellitus

  • uncontrolled esophagitis or peptic ulcer

Study Design

Total Participants: 65
Study Start date:
October 01, 2013
Estimated Completion Date:
July 31, 2016

Study Description

we planned a randomized prospective trial for cancer patients with DIH. The objective of the present study was to determine whether the rotation of corticosteroids affects the incidence and intensity of DIH without compromising the antiemetic efficacy.

Connect with a study center

  • Gyeongsang National University Hospital

    Chiram-dong, Jinju-si, Gyeongsangnam-do 660-702
    Korea, Republic of

    Site Not Available

  • Chungang University Hospital

    Dongjak-gu, Seoul 156-755
    Korea, Republic of

    Site Not Available

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