Randomized Comparison of Continuous and Intermittent Heparin Infusion During Catheter Ablation of Atrial Fibrillation

Last updated: April 13, 2016
Sponsor: Yong Seog Oh
Overall Status: Completed

Phase

3

Condition

Arrhythmia

Cardiac Disease

Chest Pain

Treatment

N/A

Clinical Study ID

NCT01935557
COHERE
  • All Genders

Study Summary

Optimal anticoagulation using heparin with close attention to maintain therapeutic dosing during the procedure is important.

Randomized comparison of continuous and intermittent heparin infusion during catheter ablation of Atrial Fibrillation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Atrial Fibrillation, Radiofrequency catheter ablation scheduled

Exclusion

Exclusion Criteria:

  • Clinical trial denied

Study Design

Total Participants: 296
Study Start date:
December 01, 2012
Estimated Completion Date:
December 31, 2015

Study Description

Intravenous heparin was used during the procedure to prevent catheter-induced thrombosis.

heparin is administered during the procedure to achieve recommended activation clotting times (ACT) values, typically >300 seconds to prevent thromboemboli during the procedure.

Most of the practitioners was that ACT level should be checked at 30- to 60-minute intervals and then have injected intermittently.

intermittent heparin infusion, concentration is great changed because the heparin has 30minutes half-period.

researchers postulate that a constant therapeutic concentrations would be beneficial to continuous infusion than intermittent infusion.

Connect with a study center

  • Seoul st. mary's hospital

    Seoul,
    Korea, Republic of

    Site Not Available

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