A Registry for Participants With Chronic Hypoparathyroidism

Last updated: October 8, 2024
Sponsor: Takeda
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Hypoparathyroidism

Treatment

No intervention

Clinical Study ID

NCT01922440
PAR-R13-001
EUPAS16927
  • All Genders

Study Summary

The main aim of this study is to find out the long-term safety and effectiveness profile of recombinant human parathyroid hormone (1-84) (rhPTH[1-84]) treatment in participants with chronic hypoparathyroidism under conditions of routine clinical practice.

Participants will be treated according to their clinic's standard practice determined by the treating doctors. Each participant will fill out a study questionnaire during a routine doctor visit.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Participants diagnosed with chronic hypoparathyroidism, that is, hypoparathyroidismwith a duration of longer than 6 months, including:
  1. Adult participants (greater than or equal to [>=] 18 years of age) who arereceiving for chronic hypoparathyroidism any of the following options: standardtherapy, standard therapy plus rhPTH(1-84), or rhPTH(1-84) therapy alone.

  2. Pediatric participants (less than [<] 18 years of age) who are receiving forchronic hypoparathyroidism any of the following options: standard therapy,standard therapy plus rhPTH(1-84), or rhPTH(1-84) therapy alone.

Exclusion

Exclusion Criteria:

  • Participants or legally acceptable representatives unable to provide informedconsent.

  • Participants using rhPTH(1-34) or who used rhPTH(1-34) for more than 2 years areexcluded. Participants who had been treated with rhPTH(1-34) within 3 months ofenrollment are also excluded as are participants currently using rhPTH(1-34).

FOR US SITES ONLY: Participants treated with rhPTH(1-84) prior to the US recall may use rhPTH(1-34) only while rhPTH(1-84) is unavailable due to the recall.

  • Participants currently enrolled in an interventional clinical study (whether or notthe study is related to hypoparathyroidism); note that this does not includeparticipants enrolled in other observational registries.

  • History of hypoparathyroidism resulting from impaired responsiveness to PTH (pseudohypoparathyroidism).

Study Design

Total Participants: 1339
Treatment Group(s): 1
Primary Treatment: No intervention
Phase:
Study Start date:
July 30, 2013
Estimated Completion Date:
November 30, 2034

Connect with a study center

  • Medizinische Universitaetsklinik Graz, Universitätsklinik Für Innere Medizin Graz

    Graz, 8036
    Austria

    Site Not Available

  • AKH Wien, Universitaetsklinik fuer Innere Medizin III

    Wien, 1090
    Austria

    Site Not Available

  • Nova Scotia Health Authority

    Halifax, Nova Scotia B3H 2Y9
    Canada

    Site Not Available

  • McMaster University

    Oakville, Ontario L6J IX8
    Canada

    Site Not Available

  • Aallborg University Hospital

    Aalborg, 9000
    Denmark

    Site Not Available

  • Aarhus Universitetshospital

    Aarhus N, 8200
    Denmark

    Site Not Available

  • Aarhus University Hospital

    Aarhus-C, DK8000
    Denmark

    Site Not Available

  • Nordsjaellands Hospital - Hillerod

    Hilleroed, 3400
    Denmark

    Site Not Available

  • Nordsjællands Hospital - Hillerød Hospital

    Hillerød, 3400
    Denmark

    Site Not Available

  • Regions Hospitalet Viborg

    Viborg, 8800
    Denmark

    Site Not Available

  • Diakonie-Klinikum Stuttgart

    Stuttgart, Baden-Wuerttemberg 70176
    Germany

    Site Not Available

  • Medizinische Hochschule Hannover

    Hannover, Lower Saxony 30625
    Germany

    Site Not Available

  • University Hospital Duesseldorf

    Dusseldorf, Nordrhein-Westfalen 40225
    Germany

    Site Not Available

  • University of Leipzig

    Leipzig, Sachsen 04103
    Germany

    Site Not Available

  • Universitaetsklinik Aachen

    Aachen, 52074
    Germany

    Site Not Available

  • Charite-Universitiitsmedizin Berlin (CCM)

    Berlin, 10117
    Germany

    Site Not Available

  • Praxis an der Kaiserreiche

    Berlin, 12159
    Germany

    Site Not Available

  • Medizinische Fakultaet Carl Gustav Carus Technische Universitaet Dresden

    Dresden, 01307
    Germany

    Site Not Available

  • Endokrinologikum Frankfurt

    Frankfurt, 60596
    Germany

    Site Not Available

  • Endokrinologikum Frankfurt Am Main

    Frankfurt Am Main, 60596
    Germany

    Site Not Available

  • MVZ endokrinologikum Göttingen

    Göttingen, 37075
    Germany

    Site Not Available

  • Universitaet Zur Luebeck

    Luebeck, 23538
    Germany

    Site Not Available

  • Universität Zur Lübeck

    Lübeck, 23538
    Germany

    Site Not Available

  • Medicover Neuroendokrinologie MVZ

    Muenchen, 81667
    Germany

    Site Not Available

  • Medicover Neu-Ulm Mvz

    Neu-Ulm, 89231
    Germany

    Site Not Available

  • Medicover Oldenburg MVZ

    Oldenburg, 26122
    Germany

    Site Not Available

  • Medicover Saarbuecken Mvz

    Saarbruecken, 66111
    Germany

    Site Not Available

  • Endokrinologie Zentrum Ulm

    Ulm, 89075
    Germany

    Site Not Available

  • Universitaetsklinikum Wuerzburg

    Wuerzburg, 97080
    Germany

    Site Not Available

  • Universitätsklinikum Würzburg

    Würzburg, 97080
    Germany

    Site Not Available

  • General Hospital Of Athens - Korgialenio-Benakio E.E.S.

    Athens, 11526
    Greece

    Site Not Available

  • General Hospital of Athens Alexandra

    Athens, 11528
    Greece

    Site Not Available

  • General Hospital of Athens Georgios Gennimatas

    Athens, 11527
    Greece

    Site Not Available

  • AHEPA University General Hospital of Thessaloniki

    Thessaloniki, 54636
    Greece

    Site Not Available

  • Hippokrateion General Hospital of Thessaloniki

    Thessaloniki, 54642
    Greece

    Site Not Available

  • Azienda Ospedaliero-Universitaria Careggi

    Firenze, FI 50139
    Italy

    Site Not Available

  • Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico

    Milano, MI 20122
    Italy

    Site Not Available

  • Azienda Ospedaliera San Giovanni Addolorata

    Roma, RM 00184
    Italy

    Site Not Available

  • Azienda Ospedaliero-Universitaria Citta della Salute e della Scienza - Ospedale Molinette

    Torino, TO 10126
    Italy

    Site Not Available

  • Haukeland University Hospital

    Bergen, 5012
    Norway

    Site Not Available

  • Spesialistsentret Pilestredet Park

    Oslo, 0176
    Norway

    Site Not Available

  • Hospital Del Mar

    Barcelona, 08003
    Spain

    Site Not Available

  • Hospital Universitario San Cecilio

    Granada, 18016
    Spain

    Site Not Available

  • Hospital Universitario 12 de Octubre

    Madrid, 28041
    Spain

    Site Not Available

  • Universitetssjukhuset I Linkoping

    Linkoping, 58185
    Sweden

    Site Not Available

  • Universitetssjukhuset I Orebro

    Orebro, 70185
    Sweden

    Site Not Available

  • Karolinska Universitetssjukhuset Solna

    Stockholm, 17176
    Sweden

    Site Not Available

  • Akademiska Sjukhuset - Uppsala University Hospital

    Uppsala, 75185
    Sweden

    Site Not Available

  • Universitetssjukhuset I Örebro

    Örebro, 701 8
    Sweden

    Site Not Available

  • Queen Elizabeth Hospital-Mindelsohn Way

    Birmingham, England B15
    United Kingdom

    Site Not Available

  • University of Hospitals of Leicester

    Leicester, LE1 5WW
    United Kingdom

    Site Not Available

  • Norfolk And Norwich University Hospital - Norwich Medical School

    Norwich, NR4 7UQ
    United Kingdom

    Site Not Available

  • University of Alabama at Birmingham

    Birmingham, Alabama 35205
    United States

    Site Not Available

  • University of Arizona Medical Center

    Tucson, Arizona 85714
    United States

    Site Not Available

  • Cedars-Sinai Medical Center

    Los Angeles, California 90048
    United States

    Site Not Available

  • Children's Hospital Los Angeles

    Los Angeles, California 90027
    United States

    Site Not Available

  • Dr. Joselito Cabaccan

    San Jose, California 95148
    United States

    Site Not Available

  • University of Colorado Hospital

    Aurora, Colorado 80045
    United States

    Site Not Available

  • Yale University

    New Haven, Connecticut 06510
    United States

    Site Not Available

  • Hanson Clinical Research Center

    Port Charlotte, Florida 33952
    United States

    Site Not Available

  • Thyroid & Endocrine Center of Florida

    Sarasota, Florida 34239
    United States

    Site Not Available

  • East-West Medical Research Institute

    Honolulu, Hawaii 96814
    United States

    Site Not Available

  • Suburban Endocrinology & Diabetes

    Arlington Heights, Illinois 60005
    United States

    Site Not Available

  • University of Chicago Medical Center

    Chicago, Illinois 60637
    United States

    Site Not Available

  • Northshore University Health System

    Evanston, Illinois 60201
    United States

    Site Not Available

  • Loyola University Medical Center

    Maywood, Illinois 60153
    United States

    Site Not Available

  • Indiana University Hospital

    Indianapolis, Indiana 46202
    United States

    Site Not Available

  • Tilak Mallik, MD F.A.C.E., LCC

    Marrero, Louisiana 70072
    United States

    Site Not Available

  • Medstar Union Memorial Hospital

    Baltimore, Maryland 21218
    United States

    Site Not Available

  • Model Clinical Research

    Baltimore, Maryland 21204
    United States

    Site Not Available

  • Boston Medical Center

    Boston, Massachusetts 02118
    United States

    Site Not Available

  • Brigham and Women's Hospital

    Boston, Massachusetts 02115
    United States

    Site Not Available

  • Harvard Medical School

    Boston, Massachusetts 02115
    United States

    Site Not Available

  • Massachusetts General Hospital

    Boston, Massachusetts 02114
    United States

    Site Not Available

  • University of Minnesota

    Minneaplis, Minnesota 55455
    United States

    Site Not Available

  • University of Minnesota

    Minneapolis, Minnesota 55455
    United States

    Site Not Available

  • Mayo Clinic - Rochester

    Rochester, Minnesota 55905
    United States

    Site Not Available

  • University of Missouri

    Columbia, Missouri 65212
    United States

    Site Not Available

  • Diabetes & Endocrine Associates, Methodist Physicians Clinic Diabetes and Endocrine Specialists

    Omaha, Nebraska 68114
    United States

    Site Not Available

  • Palm Research Center, Inc.

    Las Vegas, Nevada 89128
    United States

    Site Not Available

  • Northern Nevada Endocrinology

    Reno, Nevada 89511
    United States

    Site Not Available

  • Rutgers Robert Wood Johnson Medical School

    New Brunswick, New Jersey 08901
    United States

    Site Not Available

  • Rutgers-Robert Wood Johnson Medical School

    New Brunswick, New Jersey 08901
    United States

    Site Not Available

  • Albany Med Endocrine Specialists

    Albany, New York 12206
    United States

    Site Not Available

  • Brokhin Medical PC

    Brooklyn, New York 11223
    United States

    Site Not Available

  • Columbia University Medical Center

    New York, New York 10032
    United States

    Site Not Available

  • Gerald Friedman Diabetes Institute

    New York, New York 10022
    United States

    Site Not Available

  • Endocrine Associates of Long Island, P.C.

    Smithtown, New York 11787
    United States

    Site Not Available

  • University Physicians Group Research Division

    Staten Island, New York 10301
    United States

    Site Not Available

  • State University Of New York Upstate Medical University

    Syracuse, New York 13214
    United States

    Site Not Available

  • Mecklenburg Medical Group

    Charlotte, North Carolina 28211
    United States

    Site Not Available

  • Physicians East, PA

    Greenville, North Carolina 27834
    United States

    Site Not Available

  • Cleveland Clinic

    Cleveland, Ohio 44195
    United States

    Site Not Available

  • Ohio Health Research Institute

    Columbus, Ohio 43214
    United States

    Site Not Available

  • Ohio State University Wexner Medical Center

    Columbus, Ohio 43210
    United States

    Site Not Available

  • Endocrinology Associates of Armstrong

    Indiana, Pennsylvania 15701
    United States

    Site Not Available

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania 19104
    United States

    Site Not Available

  • Thomas Jefferson University

    Philadelphia, Pennsylvania 76307
    United States

    Site Not Available

  • Alleghany General Hospital

    Pittsburgh, Pennsylvania 15212
    United States

    Site Not Available

  • Hallett Center for Diabetes and Endocrinology

    East Providence, Rhode Island 02914
    United States

    Site Not Available

  • University of South Carolina

    Columbia, South Carolina 29203
    United States

    Site Not Available

  • Texas Diabetes and Endocrinology, P.A.

    Austin, Texas 78731
    United States

    Site Not Available

  • Thyroid Endocrinology and Diabetes

    Dallas, Texas 75208
    United States

    Site Not Available

  • Academy of Diabetes Thyroid and Endocrine

    El Paso, Texas 79935
    United States

    Site Not Available

  • Diabetes and Thyroid Center of Fort Worth, PLLC

    Fort Worth, Texas 76132
    United States

    Site Not Available

  • University of Vermont

    South Burlington, Vermont 05403
    United States

    Site Not Available

  • University of Wisconsin

    Madison, Wisconsin 53792
    United States

    Site Not Available

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