Can Genetics Predict Treatment Response to a Computerized Self-help Program for Depression?

Last updated: November 6, 2015
Sponsor: University of Texas at Austin
Overall Status: Completed

Phase

N/A

Condition

Depression

Depression (Major/severe)

Affective Disorders

Treatment

N/A

Clinical Study ID

NCT01818453
2013-01-0025
  • Ages 18-55
  • All Genders

Study Summary

The goal of this project is to determine whether genetic information can be used to predict response to an internet-based treatment of depression. Several studies now indicate that completing an internet-based treatment for depression, called Deprexis, can significantly improve symptoms of depression. However, not everyone improves. The purpose of this study is to determine whether genetic profile can predict who is likely to improve.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • English-speaking

  • Have reliable access to the internet (i.e., dialup or broadband access)

  • Be willing to donate saliva for DNA research

  • Have a current symptoms of depression

  • Be stable on medication and/or therapy (i.e. no changes within 2 weeks of study entry)

Exclusion

Exclusion Criteria:

  • Any diagnosis of a psychotic or bipolar disorder

  • Meeting for alcohol/drug dependence in the past year

  • Having current suicidal risk warranting crisis intervention

Study Design

Total Participants: 500
Study Start date:
March 01, 2013
Estimated Completion Date:
November 30, 2015

Connect with a study center

  • The University of Texas at Austin

    Austin, Texas 78713
    United States

    Site Not Available

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