Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository

Inclusion Criteria:

1. Patient must have a clinical diagnosis of morphea confirmed by the primaryinvestigator and by histopathological examination.

2. Ages 0-90 years old

3. Children must weigh more than 20 lbs. in order to satisfy Children's Medical Centerpolicy for the maximum amount of blood drawn in a 24 hour period.

4. Patient or legal guardian must be able to speak and read at a 6th grade readinglevel.

5. Both male and female patients will be eligible

6. All races and ethnic backgrounds will be included

7. Relationships to proband: All patients with morphea will be included. A patient'sfamily history will be reviewed and if there is a family history of morphea orsystemic sclerosis then we will give the study patient the investigator's contactinformation and ask the family member to call the study team to answer any questionsand enroll them in the study if they choose to do so.

8. Ability to give informed consent: Patients must be able to give informed consent orthey will give assent with parent or guardian consent as a minor to be a part of themorphea registry.

Exclusion Criteria:

• Patients who have been coded as morphea (701.0), but do not have morphea/localizedscleroderma (examples: steroid atrophy, acquired keratoderma, keloids, nephrogenicfibrosing dermopathy, systemic sclerosis, lichen sclerosis)