Can Therapy Alter CNS Processing of Chronic Pain: A Longitudinal Study

Last updated: February 19, 2013
Sponsor: University of Vermont
Overall Status: Trial Status Unknown

Phase

N/A

Condition

Chronic Pain

Pain

Treatment

N/A

Clinical Study ID

NCT01794988
R01AR059674-03
R01AR059674-03
  • Ages 18-75
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The purpose of this study is to investigate whether a psycho-therapeutic approach, group Cognitive Behavioral Therapy (CBT) plus a relapse prevention program, Therapeutic Interactive Voice Response (TIVR), modifies the dysfunctional sensory, emotional, and cognitive neural circuitry associated with chronic pain.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • At least 12 months of muscular-skeletal, non-neuropathic pain

Exclusion

Exclusion Criteria:

  • Malignancy causing or influencing chronic pain

  • Radiation or chemotherapy, or metastatic cancer of any type

  • Reflex Sympathetic Dystrophy (RSD) and/or neuropathic pain

  • Neurological disorders such as epilepsy or stroke, or other medical conditions

  • Psychiatric disorders

  • Opioid medication use for pain management

  • Past year history of illicit drug use that can result in altered cognition

  • Pregnancy

  • Exceeding weight limit of the MRI scanner

  • Incompatible implants due to MRI safety

  • Awaiting pain related surgical procedure

  • Involved in pain-related litigation

Study Design

Total Participants: 120
Study Start date:
July 01, 2010
Estimated Completion Date:

Connect with a study center

  • University of Vermont College of Medicine, MindBody Medicine Clinic

    Burlington, Vermont 05401
    United States

    Active - Recruiting

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