Evaluation of the Six Minute Walk Test and Other Instruments in Heart Failure

Last updated: August 5, 2014
Sponsor: Federal University of Uberlandia
Overall Status: Completed

Phase

N/A

Condition

Chest Pain

Heart Failure

Hyponatremia

Treatment

N/A

Clinical Study ID

NCT01736137
dont have
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The purpose of this study is to assess functional capacity, quality of life and functioning of the autonomic nervous system in heart failure patients on beta-blocker treatment. The study hypothesis is that subjects who walk less distance, have lower quality of life and reduced heart rate variability during the six minute walk test.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Both sexes

  • Different etiologies of Heart Failure

  • Functional class I - III (NYHA)

  • Left ventricular ejection fraction (LVEF) ≤ 50%

  • No history of previous cardiac surgery

  • In return for medical evaluation at the Amelio Marques Clinic, Hospital de Clinicas,Federal University of Uberlândia scheduled for the period from October 2012 to January 2013

  • Clinical stability observed by: heart rate, respiratory rate, blood pressure andarterial oxygen saturation

Exclusion

Exclusion Criteria:

  • Bad cognition compromising the understanding of tests

  • Physical disability that compromise the performance in walk test

  • Aortic aneurysm or any aortic deformity

  • Patients with signs or symptoms of transient myocardial ischemia with angina pectorisand/or class IV by the Canadian Cardiovascular Society Classification

  • Anomalous pressure behavior with hypertension > 180/100 mmHg

  • Orthostatic hypotension (decrease > 15 mmHg ) with symptoms

  • Arrhythmia with presence of complex ventricular extra systoles

  • Tachycardia sinus at rest (HR > 120 beats/min)

  • Atrioventricular block of 2nd or 3rd degree

  • Subjects with pacemakers or implantable cardioverter-defibrillator (ICD)

  • Functional class IV by the New York Heart Association

  • Chronic organ dysfunction such as renal failure, respiratory or liver disease

  • Active neoplasia over the past five years

  • Commitment as general weakness, fever, other limiting factors (psychological,musculoskeletal)

  • Feeling sick before the beginning of the Six minute walk test: intolerable angina ordyspnea, cramps in legs, staggering gait, excessive sweating (diaphoresis), pallor orashen skin or SpO2 below 85%

  • Voluntary desire of the patient to withdraw from research

Study Design

Total Participants: 17
Study Start date:
November 01, 2011
Estimated Completion Date:
February 28, 2014

Study Description

Heart failure and its treatment result in symptoms such as pulmonary or systemic congestion causing impairment to the effort, psychological and social commitment, and impact on quality of life.

Connect with a study center

  • Amelio Marques Clinic

    Uberlandia, Minas Gerais 38405320
    Brazil

    Site Not Available

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