Comparison of Desloratadine Associated With Prednisolone (Tablet)Versus Dexchlorpheniramine Associated With Betamethasone (Tablet) for Adult Persistent Allergic Rhinitis Treatment

Inclusion Criteria:

• Signed Consent of the patient;

• Clinical diagnosis of moderate - severe persistent allergic rhinitis according to ARIAclassification(Allergic Rhinitis and Its Impact on Asthma);

• Adults aged ≥ 18 years old;

• Evidence of sensitization to aeroallergens in examination (immediate skin tests orserum specific IgE) in the 12 months prior to inclusion.

Exclusion Criteria:

• Decongestants dependent patients or patients receiving allergen specificimmunotherapy;

• Patients who were in use of oral antihistamines or decongestants in the past 15 days;

• Patients who were treated with systemic corticosteroids in the last month;

• Patients on treatment with monoamine oxidase inhibitors (MAOIs);

• Patients with history of hypersensitivity to any of the formula compounds;

• Patients with any clinically significant disease that in the investigator opinion cannot participate in the study

• Patients who have uncontrolled asthma, chronic sinusitis, drug related rhinitis andnasal anatomic abnormalities.

• Participation in clinical trial in 30 days prior to study entry;