Point-of-Care Ultrasound in the Emergency Department Evaluation of Syncope

Last updated: June 29, 2016
Sponsor: Yale University
Overall Status: Terminated

Phase

N/A

Condition

Low Blood Pressure (Hypotension)

Dizzy/fainting Spells

Cataplexy

Treatment

N/A

Clinical Study ID

NCT01671371
1110009227
  • Ages > 18
  • All Genders

Study Summary

The purpose of this study is to determine whether point-of-care (bedside) ultrasound assists physicians in the evaluation and management of patients with syncope.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18 years and older presenting to the ED with acute syncope (defined as transient lossof consciousness) or near syncope (sensation of impending but not actual loss ofconsciousness) as a reason for ED visit.

Exclusion

Exclusion Criteria:

  • persistent altered mental status

  • alcohol or illicit drug-related loss of consciousness

  • definite seizure, and transient loss of consciousness caused by head trauma.

Study Design

Total Participants: 45
Study Start date:
July 01, 2012
Estimated Completion Date:
July 31, 2013

Study Description

Syncope is one of the more common presentations to the Emergency Department, representing between 1.2-1.5% of all evaluated patients and up to 6% of admissions. Due to an often broad and overlapping differential diagnosis, syncope represents a disease entity that often requires extensive workup. This typically involves laboratory tests, EKGs, x-rays, computed tomography, or other studies that are costly, time-consuming, and, in the case of diagnostic imaging, frequently involves ionizing radiation. Yet, despite extensive testing, an exact diagnosis is not made in up to 50% of cases.

Cardiac causes of syncope include myocardial infarction, pericardial effusion, volume depletion, arrhythmia, among other entities, many of which are life threatening. Echocardiography (cardiac ultrasound) has been used for inpatient syncope evaluations for several decades. In the Emergency Department, echocardiography is currently being used at the point-of-care (POC) in a limited and focused approach to a variety of conditions. However, POC ultrasound has never been systematically evaluated as a diagnostic or prognostic tool specifically for syncope in the Emergency Department. We aim to determine if an ultrasound-based protocol is effective as an adjunct in the evaluation of syncope. Our research study will examine the utility of POC ultrasound in the diagnosis, imaging and laboratory utilization, and prognosis of syncope in the Emergency Department.

Connect with a study center

  • Yale New Haven Hospital

    New Haven, Connecticut 06519
    United States

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.