Comparison of the Effect of Eprosartan and Eprosartan Mesylate on Blood Pressure in Essential Hypertension

Last updated: July 18, 2014
Sponsor: Abbott
Overall Status: Completed

Phase

3

Condition

Vascular Diseases

High Blood Pressure (Hypertension)

Diabetes And Hypertension

Treatment

N/A

Clinical Study ID

NCT01631227
M13-385
2010-019432-12
  • Ages > 18
  • All Genders

Study Summary

Aim of this study is to compare the blood pressure lowering effect of a new drug formulation of eprosartan. Eprosartan belongs to a class of blood pressure lowering agents used worldwide since years with proven efficacy. The new formulation is compared to the currently marketed eprosartan tablet. Equivalent efficacy in blood pressure lowering effects should be demonstrated.

Eligibility Criteria

Inclusion

Inclusion Criteria

  • Males or females with essential hypertension, blood pressure values between 140 mmHg and 179 mmHg systolic and between 90 mmHg and 109 mmHg diastolic

  • Given written informed consent prior to starting the study

Exclusion Criteria

  • Women with childbearing potential, breast feeding or pregnant;

  • Inability to discontinue all prior antihypertensive medication;

  • Secondary hypertension

  • Severe hypertension

  • Severe diabetes mellitus (HbA1c greater 8.5%)

Study Design

Total Participants: 665
Study Start date:
June 01, 2012
Estimated Completion Date:
April 30, 2013

Connect with a study center

  • Site Reference ID/Investigator# 74062

    Berlin, 12627
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 74066

    Bochum, 44787
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 74065

    Dresden, 01067
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 93513

    Dresden, 01307
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 93495

    Essen, 45355
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 74060

    Frankfurt, 60596
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 93515

    Frankfurt, 60594
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 74063

    Goerlitz, 02826
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 93494

    Hamburg, 22143
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 93493

    Karlsruhe, 76199
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 74061

    Leipzig, 04103
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 74064

    Magdeburg, 39104
    Germany

    Site Not Available

  • Site Reference ID/Investigator# 93514

    Nuremberg, 90402
    Germany

    Site Not Available

  • Site reference ID/Investigator # 82515

    Barnaul, 656055
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82520

    Kazan, 420012
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82493

    Kemerovo, 650002
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82516

    Kemerovo, 650055
    Russian Federation

    Site Not Available

  • Site refernce ID/Investigator # 82521

    Krasnodar, 350086
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82494

    Novosibirsk, 630047
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82495

    Novosibirsk, 630008
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82525

    Novosibirsk, 630068
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82517

    St. Petersburg, 194044
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82518

    St. Petersburg, 198260
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82519

    St. Petersburg, 198205
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82522

    St. Petersburg, 192283
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82524

    St. Petersburg, 197022
    Russian Federation

    Site Not Available

  • Site reference ID/Investigator # 82527

    St. Petersburg, 199106
    Russian Federation

    Site Not Available

  • Site reference ID/Investiragor # 82523

    St. Petersburg, 197022
    Russian Federation

    Site Not Available

  • Site Reference ID/Investigator# 74057

    Birmingham, B15 2SQ
    United Kingdom

    Site Not Available

  • Site Reference ID/Investigator# 74059

    Cardiff, CF14 5GJ
    United Kingdom

    Site Not Available

  • Site Reference ID/Investigator# 74056

    Chorley, PR7 7NA
    United Kingdom

    Site Not Available

  • Site Reference ID/Investigator# 74054

    Glasgow, G20 0SP
    United Kingdom

    Site Not Available

  • Site reference ID/Investigator # 95456

    Glasgow, G45 9AW
    United Kingdom

    Site Not Available

  • Site Reference ID/Investigator# 74053

    Liverpool, L22 0LG
    United Kingdom

    Site Not Available

  • Site reference ID/Investigator # 95457

    London, EC1M 6BQ
    United Kingdom

    Site Not Available

  • Site Reference ID/Investigator# 74055

    Manchester, M16 6SX
    United Kingdom

    Site Not Available

  • Site reference ID/Investigator # 95455

    Northwood, HA6 2RN
    United Kingdom

    Site Not Available

  • Site Reference ID/Investigator# 74058

    Reading, RG2 0TG
    United Kingdom

    Site Not Available

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