Baclofen for the Treatment of Alcohol Drinkers

Inclusion Criteria:

• Patient coming for a problem with alcohol (alcohol at high risk during the past threemonths (at least two times during each month) according to the WHO standards;. i.e.:in women more than 40 g per day or 280 g per week or more of 40 g at once; the manmore than 60 g per day or 420 g per week or more than 60 g in once, and expressing thedesire to be abstinent or to have a consumption to low level of risk).

• Volunteer to participate in the trial and having given his consent written afterappropriate information

• Patient having no treatment for the maintenance of abstinence (acamprosate,naltrexone) and the prevention of relapse (disulfiram) for at least 15 days before thebeginning of the trial

• Patient informed about the possibility of drowsiness in relation to the treatment andthe associated risks to drive vehicles (motorized or not), the use of machines (including domestic use or recreation) and the execution of tasks requiring attentionand precision

• Including woman of childbearing age (but taking effective contraception).

Exclusion Criteria:

• Patient taking already baclofen or having taken baclofen

• Patient pregnant, lactating, or childbearing years in the absence of effectivecontraception

• Patient with porphyria

• Patient with Parkinson's disease

• Patient with severe psychiatric pathology (psychosis, including schizophrenia andbipolar disorders) that can compromise the observance

• Patient with organic disease serious enough to not to allow its inclusion in the studyaccording to the opinion of the investigator

• Patient homeless

• Patient without social cover

• Patient unable to properly follow-up book, cannot commit to one year of follow-up

• Patient with a contraindication to taking baclofen (intolerance to gluten by thepresence of wheat starch

• Patient with a severe intolerance known about the lactose