Phase
Condition
Polymyositis (Inflammatory Muscle Disease)
Muscle Pain
Pain (Pediatric)
Treatment
N/AClinical Study ID
Ages 18-60 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Patients with Postpoliomyelitis Syndrome diagnosis confirmed over a year;
Electromyography test compatible with poliomyelitis;
Preserved ability to swallow medication;
Oral communication ability preserved;
Preserved ability to perform pedaling test in at least one lower limb affected byPostpoliomyelitis Syndrome;
Ability to understand information about the study and to document the decision aboutparticipating in the trial by signing the Informed Consent Form.
Exclusion
Exclusion Criteria:
History of intolerance to L-carnitine or piracetam;
Treatment with L-carnitine during the past 3 months;
Treatment with piracetam or any other nootropics pyrrolidone derivatives, during thepast three months;
Anemia (hemoglobin reference range - men 13 to 17 g/dL and women 12 to 15 g/dL);
High level of glycated hemoglobin (> 7.0%);
Electrolyte imbalance (hypokalaemia - reference potassium concentration range: 3.5 to 5.6 mmol / L);
Renal failure (creatinine reference range: 0.70 to 1.50 mg/dL);
Urinary tract infection;
Thyroid dysfunction (reference range: free T4: 0.54 to 0.67 mg/dL and TSH referencerange: 0.5 to 5.5 μUI/mL) or usual treatment with thyroid hormone supplementation;
Cardiomyopathy;
Uncontrolled hypertension;
Known or suspected autoimmune disease;
Confirmed pregnancy, or plans to get pregnant during the trial;
Depression or bipolar affective disorders with moderate to severe episodes within thelast twelve months;
Insulin-dependent diabetes mellitus;
Treatment with anticoagulant drugs over two weeks (including non-steroidalanti-inflammatory drugs (NSAIDs), warfarin, phenprocoumon, heparin);
Usual cocaine or alcohol use;
Any other condition judged by the investigator as a possibility to interfere on theparticipant's decision to be part of the study or to accomplish investigationprocedures.
Study Design
Connect with a study center
UNIFESP
São Paulo, SP
BrazilSite Not Available
UNIFESP
São Paulo, SP
BrazilSite Not Available
Not the study for you?
Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.