Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Inclusion Criteria:

• Male or female patients of any age, including minors, who have been diagnosed withaHUS

• Patients with or without an identified complement pathogenic variant oranti-complement factor antibody

• Able to give written informed consent. Patient or patient's parent/legal guardianmust be willing and able to given written informed consent and the patient (ifminor) must be willing to give written informed assent [if applicable as determinedby the central Institutional Review Boards/Independent Ethics Committees (IRB/IEC)].

• ADAMTS13 > 5%, if performed.

Exclusion Criteria:

• Hemolytic Uremic Syndrome (HUS) only due to Shiga Toxin producing Escherichia coli (STEC).

• Unable to give written informed consent. Patient or patient's parent/legal guardianunable to give written informed consent. Patient (if minor) unable to give writteninformed assent (if applicable as determined by the central Institutional ReviewBoards/Independent Ethics Committees [IRB/IEC]).