Effect of Blueberries on Cognition and Body Composition in Elderly With Mild Cognitive Decline

Phase

N/A

Condition

Mental Disability

Memory Loss

Dementia

Treatment

N/A

Clinical Study ID

NCT01515098

11-2075

Ages 65-79
All Genders
Accepts Healthy Volunteers

Study Summary

Purpose: The purpose of this study is to examine the effect of blueberry consumption on cognitive decline and body composition in humans.

Hypothesis 1: Adults with mild cognitive decline who consume blueberries will experience an improvement in cognitive abilities as measured by a standardized battery of tests, relative to those who consume a placebo.

Hypothesis 2: Adults with mild cognitive decline who consume blueberries will evidence an increase in processing speed and an improvement in memory abilities as measured in an electrophysiological paradigm and compared to those who consume a placebo.

Hypothesis 3: Daily intake of 35 g freeze-dried blueberries will improve body composition (fat mass vs. lean mass).

Hypothesis 4: Daily intake of 35 g freeze-dried blueberries will decrease oxidative stress and inflammatory markers.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Men and women age 65 and older
BMI between 18.5 and 34.5
Close individual to report memory decline

Exclusion

Exclusion Criteria:

History of central nervous system or psychiatric disorders
Dementia or Alzheimer's diagnosis
Diabetes
Smoking >20 cigarettes/day
Gastrointestinal/digestive disorders
Uncontrolled chronic disease

Study Design

January 01, 2012

March 31, 2015

Connect with a study center

Nutrition Research Institute
Kannapolis, North Carolina 28081
United States
Site Not Available

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