Efficacy of Dialectical Behavior Therapy Versus CAMS-informed Supportive Psychotherapy on Self Harming Behavior

Last updated: April 25, 2015
Sponsor: Mental Health Services in the Capital Region, Denmark
Overall Status: Completed

Phase

N/A

Condition

Mood Disorders

Suicide

Borderline Personality Disorder

Treatment

N/A

Clinical Study ID

NCT01512602
RHP-DiaS-002
  • Ages 18-65
  • All Genders

Study Summary

Purpose: The purpose of this study is to investigate the efficacy of Dialectical Behavior Therapy (DBT) versus CAMS (Collaborative Assessment and Management of Suicidality) -informed supportive psychotherapy on the risk of self-harm acts and suicide attempts in patients with self behavior and personality traits within the spectrum of borderline personality disorder.

Hypothesis: The hypothesis is 16 weeks of treatment with Dialectical Behavior Therapy (DBT) after a defined manual has a higher efficacy than CAMS-informed supportive psychotherapy on self-harm acts, suicide attempts, suicidal ideation, depressive symptoms, impulsiveness and consumption of hospital services in patients with symptoms within the spectrum of borderline personality disorder (BDP).

Method: The investigators will include 160 patients in the randomized trial to investigate whether 16 weeks of DBT-treatment as a higher efficacy than CAMS-informed supportive psychotherapy on the risk of self-harm acts and suicide attempts in patients with self-harm behavior and personality traits within the spectrum of borderline personality disorder. The trial will meet strict criteria for high quality randomized trials, and will hopefully help to establish evidence for the treatment of this patient group at higher risk of later suicide. There will be performed follow up interviews after 16 weeks, 28 weeks and 52 weeks.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18-65 years of age.

  • Newly suicide attempt within one month of the inclusion date.

  • A minimum of two characteristics in the DSM-IV Borderline Personality Disorder (BPD)

  • Informed consent.

Exclusion

Exclusion Criteria:

  • Severe depression.

  • Bipolar disorder.

  • Psychosis within the schizophrenic spectrum.

  • Anorexia Nervosa.

  • Substance abuse.

  • Mental retardation.

  • Dementia.

  • Lack of informed consent

Study Design

Total Participants: 108
Study Start date:
January 01, 2012
Estimated Completion Date:
July 31, 2014

Connect with a study center

  • Mental Health Services, Research Unit, Bispebjerg

    Copenhagen NV., 2400
    Denmark

    Site Not Available

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