Internet-based Cognitive Behavior Therapy After Myocardial Infarction

Last updated: October 27, 2020
Sponsor: Uppsala University
Overall Status: Completed

Phase

N/A

Condition

Coronary Artery Disease

Heart Defect

Angina

Treatment

N/A

Clinical Study ID

NCT01504191
U-CARE: Heart
  • Ages < 75
  • All Genders

Study Summary

The overall aim and primary objective is to evaluate the effects on level of depression and anxiety of an Internet-based CBT-program in depressed and/or anxious patients after a myocardial infarction (MI).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients younger than 75 years with a recent acute MI (< 3 months)
  • Depression and/or anxiety score of > 7 on one or both of the HADS subscales (concernsonly the intervention, not the reference group)

Exclusion

Exclusion Criteria:

  • Patients that are scheduled for a coronary artery bypass surgery (CABG)
  • Unable or unwilling to use computer or Internet
  • Difficulties in reading or understanding Swedish
  • A life expectancy of less than a year
  • Anticipated poor compliance (multi-disease, substance abuse etc.)
  • Highly depressed or suicidal (MADRS-score > 29 or MADRS item 9 > 3)

Study Design

Total Participants: 239
Study Start date:
September 01, 2013
Estimated Completion Date:
December 31, 2017

Study Description

Major or minor depressive disorders and anxiety disorders are present in many patients with cardiovascular disease (CVD) and are associated with adverse cardiovascular outcomes, even after controlling for other risk factors. 500 patients with symptoms of anxiety and/or depression after MI will be randomized either to a 14 week Internet-based CBT-program or to treatment as usual (TAU) which is the control condition. A reference group of 250 participants without depressive or anxiety symptoms will also be studied during TAU. Data will be collected before, after and 7 months after treatment. Anxiety and depression according to ratings on the Hospital Anxiety and Depression Scale (HADS) are the primary outcome measures.

Connect with a study center

  • Enköpings lassarett

    Enköping,
    Sweden

    Site Not Available

  • Falu Lasarett

    Falun, 79129
    Sweden

    Site Not Available

  • Gävle sjukhus

    Gävle, 80187
    Sweden

    Site Not Available

  • Gävle sjukhus

    Gävle, 80187
    Sweden

    Site Not Available

  • Sahlgrenska sjukhuset

    Göteborg,
    Sweden

    Site Not Available

  • Hässleholms sjukhus

    Hässleholm,
    Sweden

    Site Not Available

  • Blekinge sjukhus

    Karlskrona,
    Sweden

    Site Not Available

  • Karlstad sjukhus

    Karlstad,
    Sweden

    Site Not Available

  • Kungälvs sjukhus

    Kungälv,
    Sweden

    Site Not Available

  • Skaraborgs sjukhus

    Lidköping,
    Sweden

    Site Not Available

  • Ljungby lasarett

    Ljungby,
    Sweden

    Site Not Available

  • Skånes universitetssjukhus

    Malmö,
    Sweden

    Site Not Available

  • Mora lassarett

    Mora,
    Sweden

    Site Not Available

  • Nyköpings sjukhus

    Nyköping,
    Sweden

    Site Not Available

  • Oskarshamns sjukhus

    Oskarshamn,
    Sweden

    Site Not Available

  • Piteå älvdals sjukhus

    Piteå,
    Sweden

    Site Not Available

  • Danderyds sjukhus

    Stockholm,
    Sweden

    Site Not Available

  • Karolinska sjukhuset i Huddinge

    Stockholm,
    Sweden

    Site Not Available

  • Karolinska sjukhuset i Solna

    Stockholm,
    Sweden

    Site Not Available

  • Södersjukhuset

    Stockholm,
    Sweden

    Site Not Available

  • Länssjukhuset Sundsvall-Härnösand

    Sundsvall,
    Sweden

    Site Not Available

  • Uppsala Akademiska sjukhus

    Uppsala, 75185
    Sweden

    Site Not Available

  • Varberg sjukhus

    Varberg,
    Sweden

    Site Not Available

  • Växjö centrallasarett

    Växjö,
    Sweden

    Site Not Available

  • Universitetssjukhuset Örebro

    Örebro, 70185
    Sweden

    Site Not Available

  • Ängelholms sjukhus

    Ängelholm,
    Sweden

    Site Not Available

  • Universitetssjukhuset Örebro

    Örebro, 70185
    Sweden

    Site Not Available

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