Efficacy Study of Korean Red Ginseng to Treat Depression

Last updated: October 6, 2014
Sponsor: Korea University
Overall Status: Completed

Phase

N/A

Condition

Depression

Depression (Major/severe)

Affective Disorders

Treatment

N/A

Clinical Study ID

NCT01496248
R1105721
  • Ages 18-55
  • Female

Study Summary

The purpose of this study is to determine whether Korean Red Ginseng are effective in the treatment of the residual symptoms of depression as an adjuvant treatment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Outpatients who met Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)criteria for major depressive disorder.

  • Those who are in remission, which is defined as a MADRS score 8 on two consecutivevisits at a 4-week interval.

  • Their primary psychiatric clinician determined that they would benefit from anadjuvant treatment of Korean red ginseng for residual symptoms.

Exclusion

Exclusion Criteria:

  • Those who have a history of substance abuse or dependence within 1 month.

  • Those who have clinically significant abnormal laboratory values or any other abnormalbaseline laboratory findings considered by psychiatrists to be indicative ofconditions that might affect the study results.

  • Those who have a past history of hypersensitivity or intolerance to Korean redginseng.

  • Those who participated in clinical trials within 1 month before entering the studyentry.

  • Those who are pregnant or are breast feeding.

  • Those who have a immediate risk of harming self or others or history of suicideattempts in the year before the screening precluded inclusion in the study.

  • The patients unable/unlikely to comprehend/follow the protocol.

Study Design

Total Participants: 35
Study Start date:
August 01, 2011
Estimated Completion Date:
December 31, 2012

Study Description

Thirty-five female outpatients aging from 18 to 65 years, who were remitted from major depression with residual symptoms (Montgomery Asberg Depression Rating Scale, MADRS ≤ 12), were given Korean red ginseng at doses of 3g / day during 8 weeks.

Connect with a study center

  • Korea University Ansan Hospital

    Ansan, Gyeonggi-do 425-707
    Korea, Republic of

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.