Non-Inferiority Trial Comparing Eurofarma's Experimental Product Saccharomyces Boulardii Versus Floratil® in the Prevention of Antibiotic-Associated Diarrhea

Inclusion Criteria:

1. ICF signature;

2. The subject must agree to follow the instructions and to perform study procedures andvisits;

3. Male and female subjects between 18 and 65 years old;

4. Subjects who have scheduled a treatment or started the use of antibiotics over 24hours ago:

Exclusion Criteria:

1. Generalized infection or bacteremia;

2. Chronic gastrointestinal diseases (e.g., Crohn's Disease and Irritable BowelSyndrome);

3. Documented chronic diarrhea;

4. Acute diarrhea episode within 24 hours prior to the start of antibiotic use. Use oftube feeding (nasogastric and nasoenteral);

5. Immunodeficiency (radiotherapy or chemotherapy);

6. Use of food with probiotic properties in the last 10 days;