Treatment of Vitamin D Deficiency in Patients With Rheumatoid Arthritis

Phase

N/A

Condition

Rheumatoid Arthritis

Joint Injuries

Musculoskeletal Diseases

Treatment

N/A

Clinical Study ID

NCT01426347

VDRA

Ages 18-75
All Genders

Study Summary

The purpose of this study is to investigate the effect of vitamin D repletion on disease activity and disability in patients with rheumatoid arthritis.

The investigators hypothesize that rheumatoid arthritis (RA) patients with vitamin D deficiency have greater disease activity and disability, compared to RA patients with normal vitamin D levels. The investigators also hypothesize that vitamin D treatment in these deficient patients will result in a decrease in RA disease activity and disability.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Rheumatoid Arthritis diagnosed according to American College of Rheumatology (ACR)criteria
ages 18-75 years

Exclusion

Exclusion Criteria:

Diagnosis of any other autoimmune disease: such as Lupus, Scleroderma, Myositis, Sjogren's Syndrome, Vasculitis'
Having any of the following conditions with in the last 6 months Hypercalcemia,Hyperparathyroidism, Active tuberculosis (TB), Lymphoma or any other type of cancer,Sarcoidosis, Seizure, Stroke
Severe heart problems
Kidney failure requiring dialysis treatment
Liver failure or cirrhosis of the liver
Poorly controlled hypertension
current uncontrolled Depression, Bipolar Disorder, or other Psychiatric illness
Pregnancy

Study Design

January 01, 2009

January 31, 2012

Connect with a study center

Johns Hopkins University
Baltimore, Maryland 21224
United States
Site Not Available

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